This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LZRS ERTm RasV12
catalog :
21199
citations: 4
Reference
Lionarons D, Hancock D, Rana S, East P, Moore C, Murillo M, et al. RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. Cancer Cell. 2019;: pubmed publisher
Dendo K, Yugawa T, Nakahara T, Ohno S, Goshima N, Arakawa H, et al. Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression. Carcinogenesis. 2018;39:202-213 pubmed publisher
Kanda T, Furuse Y, Oshitani H, Kiyono T. Highly Efficient CRISPR/Cas9-Mediated Cloning and Functional Characterization of Gastric Cancer-Derived Epstein-Barr Virus Strains. J Virol. 2016;90:4383-93 pubmed publisher
Dajee M, Tarutani M, Deng H, Cai T, Khavari P. Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation. Oncogene. 2002;21:1527-38 pubmed
product information
Catalog Number :
21199
Product Name :
LZRS ERTm RasV12
article :
doi10.1038/sj.onc.1205287
id2631
pubmed_id11896581
bacterial resistance :
Ampicillin
cloning :
backboneLZRS no LacZ
backbone_mutation
backbone_origin
backbone_size11100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Retroviral
growth temp :
STBL2
origin :
37
pi :
alt_names
mouse Esr1 upstream of human HrasG12V
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5BamHI
promoter
sequencing_primer_3ATCGTCGACCACTGTGCTGG
sequencing_primer_5TGGATACACGCCGCCCACGTG
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesER, ER-alpha, ERa, ERalpha, ESR, Estr, Estra, Nr3a1
geneEsr1
id13982
aliasesC-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
geneHRAS
id3265
genbank_ids
mutationEsr1 G257R; HRasG12V ERTm bx3
nameEsR1- HRas
shRNA_sequence
size1700
species
9606
Homo sapiens
10090
Mus musculus
tags
resistance markers :
249
tags :
Low Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA