This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-miR21
catalog :
21114
citations: 9
Reference
Nonaka C, Sampaio G, Silva K, Khouri R, Macedo C, Chagas Translational Research Consortium -, et al. Therapeutic miR-21 Silencing Reduces Cardiac Fibrosis and Modulates Inflammatory Response in Chronic Chagas Disease. Int J Mol Sci. 2021;22: pubmed publisher
Arisan E, Rencüzoğulları Ö, Cieza Borrella C, Miralles Arenas F, Dwek M, Lange S, et al. MiR-21 Is Required for the Epithelial-Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells. Int J Mol Sci. 2021;22: pubmed publisher
Velagapudi S, Costales M, Vummidi B, Nakai Y, Angelbello A, Tran T, et al. Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs. Cell Chem Biol. 2018;25:1086-1094.e7 pubmed publisher
Li X, Kleeman S, Coburn S, Fumagalli C, Perner J, Jammula S, et al. Selection and Application of Tissue microRNAs for Nonendoscopic Diagnosis of Barrett's Esophagus. Gastroenterology. 2018;155:771-783.e3 pubmed publisher
Kowshik J, Mishra R, Sophia J, Rautray S, Anbarasu K, Reddy G, et al. Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis model. Sci Rep. 2017;7:2045 pubmed publisher
Casaburi I, Cesario M, Donà A, Rizza P, Aquila S, Avena P, et al. Androgens downregulate miR-21 expression in breast cancer cells underlining the protective role of androgen receptor. Oncotarget. 2016;7:12651-61 pubmed publisher
Yin S, Yu Y, Reed R. Primary microRNA processing is functionally coupled to RNAP II transcription in vitro. Sci Rep. 2015;5:11992 pubmed publisher
Peng X, Chang H, Gu Y, Chen J, Yi L, Xie Q, et al. 3,6-Dihydroxyflavone Suppresses Breast Carcinogenesis by Epigenetically Regulating miR-34a and miR-21. Cancer Prev Res (Phila). 2015;8:509-17 pubmed publisher
Hwang H, Wentzel E, Mendell J. Cell-cell contact globally activates microRNA biogenesis. Proc Natl Acad Sci U S A. 2009;106:7016-21 pubmed publisher
product information
Catalog Number :
21114
Product Name :
pcDNA3-miR21
article :
doi10.1073/pnas.0811523106
id2577
pubmed_id19359480
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1(+) (Invitrogen)
backbone_mutation
backbone_origin
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NheI
cloning_site_5NheI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMIRN21, hsa-mir-21, miR-21, miRNA21
geneMIR21
id406991
genbank_ids
mutation
namemiR-21
shRNA_sequence
size434
species
9606
Homo sapiens
tags
resistance markers :
328
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA