This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3.1/V5-His-TOPO-mir17-92
catalog :
21109
citations: 6
Reference
Martens de Kemp S, Komor M, Hegi R, Bolijn A, Tijssen M, de Groen F, et al. Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature. Neoplasia. 2022;32:100820 pubmed publisher
Dakir E, Mollinedo F. Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells. Oncotarget. 2019;10:5313-5331 pubmed publisher
Pai P, Kuo C, Ho T, Lin J, Lin D, Tsai F, et al. p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure. Cell Death Dis. 2017;8:e2990 pubmed publisher
Velagapudi S, Luo Y, Tran T, Haniff H, Nakai Y, Fallahi M, et al. Defining RNA-Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA. ACS Cent Sci. 2017;3:205-216 pubmed publisher
Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sultmann H, et al. Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells. PLoS Pathog. 2015;11:e1004712 pubmed publisher
O Donnell K, Wentzel E, Zeller K, Dang C, Mendell J. c-Myc-regulated microRNAs modulate E2F1 expression. Nature. 2005;435:839-43 pubmed
product information
Catalog Number :
21109
Product Name :
pcDNA3.1/V5-His-TOPO-mir17-92
article :
doi10.1038/nature03677
id2575
pubmed_id15944709
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1/V5-His-TOPO
backbone_mutation
backbone_originInvitrogen
backbone_size5523
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
miR17 cluster
cloning
clone_methodTOPO Cloning
cloning_site_3TOPO
cloning_site_5TOPO
promoter
sequencing_primer_3BGH reverse
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMIR17-5p, MIR91, MIRN17, MIRN91, hsa-mir-17, miR-17, miR17-3p, miRNA17, miRNA91
geneMIR17
id406952
genbank_ids
mutation
namemiR-17-92 cluster
shRNA_sequence
size1117
species
9606
Homo sapiens
tags
resistance markers :
328
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA