This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCAG-HIF1 alpha
catalog :
21101
citations: 3
Reference
Du S, Zhu L, Wang Y, Liu J, Zhang D, Chen Y, et al. SENP1-mediated deSUMOylation of USP28 regulated HIF-1α accumulation and activation during hypoxia response. Cancer Cell Int. 2019;19:4 pubmed publisher
Ambaye N, Chen C, Khanna S, LI Y, Chen Y. Streptonigrin Inhibits SENP1 and Reduces the Protein Level of Hypoxia-Inducible Factor 1? (HIF1?) in Cells. Biochemistry. 2018;57:1807-1813 pubmed publisher
Chen B, Cepko C. HDAC4 regulates neuronal survival in normal and diseased retinas. Science. 2009;323:256-9 pubmed publisher
product information
Catalog Number :
21101
Product Name :
pCAG-HIF1 alpha
article :
doi10.1126/science.1166226
id2573
pubmed_id19131628
bacterial resistance :
Ampicillin
cloning :
backbonepCAGEN
backbone_mutation
backbone_originAddgene Plasmid 11160
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Compared to GenBank reference sequence NP_001521.1 the HIF1 alpha insert in this plasmid contains C217Y & A279D mutations.
origin :
37
pi :
alt_names
HIF1A
cloning
clone_methodRestriction Enzyme
cloning_site_3NOT1
cloning_site_5NOT1
promoter
sequencing_primer_3
sequencing_primer_5pCAG-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
geneHIF1A
id3091
genbank_ids
mutation
nameHYPOXIA INDUCIBLE FACTOR 1ALPHA
shRNA_sequence
size2400
species
9606
Homo sapiens
tags
plasmid copy :
K.W. Kim, Seoul National University
resistance markers :
71
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA