This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV-myc3-HDM2
catalog :
20935
citations: 6
Reference
Cardano M, Magni M, Alfieri R, Chan S, Sabbioneda S, Buscemi G, et al. Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells. Cell Death Dis. 2023;14:197 pubmed publisher
Niu X, Cui H, Gu X, Wu T, Sun M, Zhou C, et al. Nuclear Receptor PXR Confers Irradiation Resistance by Promoting DNA Damage Response Through Stabilization of ATF3. Front Oncol. 2022;12:837980 pubmed publisher
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development. J Exp Clin Cancer Res. 2018;37:28 pubmed publisher
Chen Y, Wang D, Wu Y, Su D, Zhou T, Gai R, et al. MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. Br J Cancer. 2017;117:1192-1201 pubmed publisher
Schmidt M, Calvisi D, Clark G. NORE1A Regulates MDM2 Via ?-TrCP. Cancers (Basel). 2016;8: pubmed publisher
Zhang Y, Wolf G, Bhat K, Jin A, Allio T, Burkhart W, et al. Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway. Mol Cell Biol. 2003;23:8902-12 pubmed
product information
Catalog Number :
20935
Product Name :
pCMV-myc3-HDM2
article :
doi10.1128/MCB.23.23.8902-8912.2003
id2539
pubmed_id14612427
bacterial resistance :
Ampicillin
cloning :
backbonepCMV
backbone_mutation
backbone_originClontech
backbone_size3800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
HDM2 (MYO-32 transcript variant)
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesACTFS, HDMX, LSKB, hdm2
geneMDM2
id4193
genbank_ids
AFM80540.1
mutation
nameMdm2 p53 binding protein homolog
shRNA_sequence
size2100
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmyc3
resistance markers :
593
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA