This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
p21-pRc/CMV
catalog :
20814
citations: 5
Reference
Sevilla Montero J, Bienes Martínez R, Labrousse Arias D, Fuertes Yebra E, Ordoñez A, Calzada M. pVHL-mediated regulation of the anti-angiogenic protein thrombospondin-1 decreases migration of Clear Cell Renal Carcinoma Cell Lines. Sci Rep. 2020;10:1175 pubmed publisher
Zaremba Czogalla M, Hryniewicz Jankowska A, Tabola R, Nienartowicz M, Stach K, Wierzbicki J, et al. A novel regulatory function of CDKN1A/p21 in TNFα-induced matrix metalloproteinase 9-dependent migration and invasion of triple-negative breast cancer cells. Cell Signal. 2018;47:27-36 pubmed publisher
Labrousse Arias D, Martínez Alonso E, Corral Escariz M, Bienes Martínez R, Berridy J, Serrano Oviedo L, et al. VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1. J Cell Biol. 2017;216:835-847 pubmed publisher
Willmer T, Hare S, Peres J, Prince S. The T-box transcription factor TBX3 drives proliferation by direct repression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cell Div. 2016;11:6 pubmed publisher
Adams P, Sellers W, Sharma S, Wu A, Nalin C, Kaelin W. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol Cell Biol. 1996;16:6623-33 pubmed
product information
Catalog Number :
20814
Product Name :
p21-pRc/CMV
article :
doi
id2510
pubmed_id8943316
bacterial resistance :
Ampicillin
cloning :
backbonepRc/CMV
backbone_mutation
backbone_origin
backbone_size5448
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth temp :
DH5alpha
origin :
37
pi :
alt_names
CIP1, WAF1
cloning
clone_methodRestriction Enzyme
cloning_site_3Xba I
cloning_site_5Hind III
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1
geneCDKN1A
id1026
genbank_ids
L25610
mutationwt
namep21
shRNA_sequence
size593
species
9606
Homo sapiens
tags
resistance markers :
238
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA