This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
FUW-tetO-hMYC
catalog :
20723
citations: 17
Reference
Wang Y, Yao M, Li C, Yang K, Qin X, Xu L, et al. Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling. Exp Hematol Oncol. 2023;12:105 pubmed publisher
Chen H, Gardner E, Shah Y, Zhang K, Thakur A, Zhang C, et al. FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS. bioRxiv. 2023;: pubmed publisher
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, et al. Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration. iScience. 2022;25:105050 pubmed publisher
Roberts G, Ozkan B, Gachulincova I, O Dwyer M, Hall Ponsele E, Saxena M, et al. Dissecting OCT4 defines the role of nucleosome binding in pluripotency. Nat Cell Biol. 2021;23:834-845 pubmed publisher
Ruiz G, Valencia González H, Perez Montiel D, Muñoz F, Ocadiz Delgado R, Fernandez Retana J, et al. Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line. Stem Cells Int. 2019;2019:7683817 pubmed publisher
Galonska C, Charlton J, Mattei A, Donaghey J, Clement K, Gu H, et al. Genome-wide tracking of dCas9-methyltransferase footprints. Nat Commun. 2018;9:597 pubmed publisher
Rodríguez Madoz J, San Jose Eneriz E, Rabal O, Zapata Linares N, Miranda E, Rodriguez S, et al. Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome. PLoS ONE. 2017;12:e0190275 pubmed publisher
Nguyen P, Choo K, Huang C, Sugii S, Cheong S, Kamarul T. miR-524-5p of the primate-specific C19MC miRNA cluster targets TP53IPN1- and EMT-associated genes to regulate cellular reprogramming. Stem Cell Res Ther. 2017;8:214 pubmed publisher
Unno K, Roh M, Yoo Y, Al Shraideh Y, Wang L, Nonn L, et al. Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids. Oncotarget. 2017;8:51264-51276 pubmed publisher
Cha Y, Han M, Cha H, Zoldan J, Burkart A, Jung J, et al. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis. Nat Cell Biol. 2017;19:445-456 pubmed publisher
Wu J, Platero Luengo A, Sakurai M, Sugawara A, Gil M, Yamauchi T, et al. Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Cell. 2017;168:473-486.e15 pubmed publisher
Soppa U, Schumacher J, Florencio Ortiz V, Pasqualon T, Tejedor F, Becker W. The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation. Cell Cycle. 2014;13:2084-100 pubmed publisher
Park H, Kim D, Kim C, Mills R, Chang M, Iskow R, et al. Increased genomic integrity of an improved protein-based mouse induced pluripotent stem cell method compared with current viral-induced strategies. Stem Cells Transl Med. 2014;3:599-609 pubmed publisher
Stefos G, Soppa U, Dierssen M, Becker W. NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect. PLoS ONE. 2013;8:e67470 pubmed publisher
Park S, Riley P, Frisch S. Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-κB. Apoptosis. 2013;18:949-62 pubmed publisher
Liang Y, Agren L, Lyczek A, Walczak P, Bulte J. Neural progenitor cell survival in mouse brain can be improved by co-transplantation of helper cells expressing bFGF under doxycycline control. Exp Neurol. 2013;247:73-9 pubmed publisher
Hockemeyer D, Soldner F, Cook E, Gao Q, Mitalipova M, Jaenisch R. A drug-inducible system for direct reprogramming of human somatic cells to pluripotency. Cell Stem Cell. 2008;3:346-353 pubmed publisher
product information
Catalog Number :
20723
Product Name :
FUW-tetO-hMYC
article :
doi10.1016/j.stem.2008.08.014
id2460
pubmed_id18786421
bacterial resistance :
Ampicillin
cloning :
backboneFUW
backbone_mutation
backbone_originCarlos Lois
backbone_size8382
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth temp :
TOP10, 37C
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5LNCX
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
mutation
namec-MYC
shRNA_sequence
size1365
species
9606
Homo sapiens
tags
resistance markers :
227
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA