This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Cav2.1 EA2, R57A, R59A pMT2
catalog :
206122
citations: 1
Reference
Dahimene S, Page K, Nieto Rostro M, Pratt W, D Arco M, Dolphin A. A CaV2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant. Neurobiol Dis. 2016;93:243-56 pubmed publisher
product information
Catalog Number :
206122
Product Name :
Cav2.1 EA2, R57A, R59A pMT2
article :
doi10.1016/j.nbd.2016.05.020
id28238460
pubmed_id27260834
bacterial resistance :
Ampicillin
cloning :
backbonepMT2
backbone_mutation
backbone_originGenetics Institute Inc
backbone_size5163
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
expression of rabbit Cav2.1 calcium channel with a CaV2.1-P1217fs mutation causing a truncated protein, (EA2). R57A R59A mutations prevent dominant-negative suppression of Cav2.1 currents
origin :
37
pi :
alt_names
Cav2.1 alpha1A/EA2
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5unknown
promoterAd MLP/TPL/SV40
sequencing_primer_3GGTCGAACCATGATGGCAGC
sequencing_primer_5AGCTTGAGGTGTGGCAGGCTT
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBccA1, Cav2.1, rbA-1
geneCacna1a
id25398
genbank_ids
mutationCav2.1-P1217fs, R57A, R59A
namecacna1a
shRNA_sequence
size3792
species
10116
Rattus norvegicus
tags
plasmid copy :
Terry P. Snutch
resistance markers :
2017
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA