Luc-SIRT1 mutant 3'UTR | Addgene 20380 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

Luc-SIRT1 mutant 3'UTR

catalog :

20380

citations: 2

Reference
Ferreira D, Afonso M, Rodrigues P, Simão A, Pereira D, Borralho P, et al. c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. Mol Cell Biol. 2014;34:1100-20 pubmed publisher
Yamakuchi M, Ferlito M, Lowenstein C. miR-34a repression of SIRT1 regulates apoptosis. Proc Natl Acad Sci U S A. 2008;105:13421-6 pubmed publisher

product information

Catalog Number :

20380

Product Name :

Luc-SIRT1 mutant 3'UTR

article :

doi	10.1073/pnas.0801613105
id	2469
pubmed_id	18755897

bacterial resistance :

Ampicillin

cloning :

backbone

pMIR-REPORT

backbone_mutation

backbone_origin

backbone_size

6470

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Luciferase

growth notes :

There are mismatches between Addgene's sequence and NCBI sequence for SIRT1 UTR. Deposit is aware of these changes and doesn't think they affect function.

origin :

pi :

alt_names

sirtuin (silent mating type information regulation 2 homolog) 1

cloning

clone_method	Restriction Enzyme
cloning_site_3	SacI
cloning_site_5	PmeI
promoter
sequencing_primer_3
sequencing_primer_5	N/A
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	SIR2, SIR2L1, SIR2alpha
gene	SIRT1
id	23411

genbank_ids

mutation

mutant 3'UTR of SIRT1

name

SIRT1

shRNA_sequence

size

1420

species

9606

Homo sapiens