This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Lyn-FKBP-FKBP-CFP (LF2C)
catalog :
20149
citations: 4
Reference
Komori T, Kuwahara T, Fujimoto T, Sakurai M, Koyama Honda I, Fukuda M, et al. Phosphorylation of Rab29 at Ser185 regulates its localization and role in the lysosomal stress response in concert with LRRK2. J Cell Sci. 2023;136: pubmed publisher
Courtney T, Hankinson C, Horst T, Deiters A. Targeted protein oxidation using a chromophore-modified rapamycin analog. Chem Sci. 2021;12:13425-13433 pubmed publisher
Muntean B, Martemyanov K. Association with the Plasma Membrane Is Sufficient for Potentiating Catalytic Activity of Regulators of G Protein Signaling (RGS) Proteins of the R7 Subfamily. J Biol Chem. 2016;291:7195-204 pubmed publisher
Inoue T, Heo W, Grimley J, Wandless T, Meyer T. An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways. Nat Methods. 2005;2:415-8 pubmed
product information
Catalog Number :
20149
Product Name :
Lyn-FKBP-FKBP-CFP (LF2C)
article :
doi10.1038/nmeth763
id2411
pubmed_id15908919
bacterial resistance :
Kanamycin
cloning :
backboneECFP-C1
backbone_mutation
backbone_originClontech
backbone_size4733
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Addgene sequencing results show L97Q variant in second FKBP. It is unknown whether this variant affects function.
origin :
37
pi :
alt_names
FKBP12
cloning
clone_methodRestriction Enzyme
cloning_site_3BamH1
cloning_site_5EcoR1
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesFKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
geneFKBP1A
id2280
genbank_ids
mutationSee depositor comments below.
nameLyn-FKBP-FKBP-CFP
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
336
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA