This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMSCVpuro-Flag-cMyc T58A
catalog :
20076
citations: 8
Reference
Scarpa M, Kapoor S, Tvedte E, Doshi K, Zou Y, Singh P, et al. Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication. Oncotarget. 2021;12:1763-1779 pubmed publisher
Scarpa M, Singh P, Bailey C, Lee J, Kapoor S, Lapidus R, et al. PP2A-activating drugs enhance FLT3 inhibitor efficacy through AKT inhibition-dependent GSK-3β-mediated c-Myc and Pim-1 proteasomal degradation. Mol Cancer Ther. 2021;: pubmed publisher
Rockfield S, Kee Y, Nanjundan M. Chronic iron exposure and c-Myc/H-ras-mediated transformation in fallopian tube cells alter the expression of EVI1, amplified at 3q26.2 in ovarian cancer. Oncogenesis. 2019;8:46 pubmed publisher
Yi J, Liu C, Tao Z, Wang M, Jia Y, Sang X, et al. MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer. EBioMedicine. 2019;43:225-237 pubmed publisher
Vaseva A, Blake D, Gilbert T, Ng S, Hostetter G, Azam S, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018;34:807-822.e7 pubmed publisher
Rockfield S, Flores I, Nanjundan M. Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells. Oncotarget. 2018;9:5344-5367 pubmed publisher
Liu P, Cheng H, Santiago S, Raeder M, Zhang F, Isabella A, et al. Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms. Nat Med. 2011;17:1116-20 pubmed publisher
Aasen T, Raya A, Barrero M, Garreta E, Consiglio A, Gonzalez F, et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol. 2008;26:1276-84 pubmed publisher
product information
Catalog Number :
20076
Product Name :
pMSCVpuro-Flag-cMyc T58A
article :
doi10.1038/nbt.1503
id2393
pubmed_id18931654
bacterial resistance :
Ampicillin
cloning :
backbonepMSCVpuro
backbone_mutation
backbone_originClontech
backbone_size6300
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5XhoI
promoter
sequencing_primer_3MSCV-rev
sequencing_primer_5pBABE 5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
mutationT58A
namecMyc
shRNA_sequence
size1300
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
24
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA