This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-myc3-CUL2
catalog :
19892
citations: 10
Reference
Wang Q, Li H, Tajima K, Verkerke A, Taxin Z, Hou Z, et al. Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature. 2022;609:151-158 pubmed publisher
Yin C, Lui E, Jiang T, Qi R. Proteolysis of γ-tubulin small complex proteins is mediated by the ubiquitin-proteasome system. FEBS Lett. 2021;595:1987-1996 pubmed publisher
Bayraktar G, Yuanxiang P, Confettura A, Gomes G, Raza S, Stork O, et al. Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Neuropsychopharmacology. 2020;45:2120-2130 pubmed publisher
Faull S, Lau A, Martens C, Ahdash Z, Hansen K, Yébenes H, et al. Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun. 2019;10:3814 pubmed publisher
Zhou W, Xu J, Tan M, Li H, Li H, Wei W, et al. UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F. Mol Cell. 2018;70:1008-1024.e6 pubmed publisher
Gu Q, Zhang Z, Gertzen C, Haussinger D, Gohlke H, Munk C. Identification of a Conserved Interface of Human Immunodeficiency Virus Type 1 and Feline Immunodeficiency Virus Vifs with Cullin 5. J Virol. 2018;92: pubmed publisher
Mudhasani R, Tran J, Retterer C, Kota K, Whitehouse C, Bavari S. Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase. PLoS Pathog. 2016;12:e1005437 pubmed publisher
Pentecost M, Vashisht A, Lester T, Voros T, Beaty S, Park A, et al. Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS Pathog. 2015;11:e1004739 pubmed publisher
Cukras S, Morffy N, Ohn T, Kee Y. Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases. PLoS ONE. 2014;9:e101844 pubmed publisher
Ohta T, Michel J, Schottelius A, Xiong Y. ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell. 1999;3:535-41 pubmed
product information
Catalog Number :
19892
Product Name :
pcDNA3-myc3-CUL2
article :
doi10.1016/S1097-2765(00)80482-7
id2345
pubmed_id10230407
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3-myc3
backbone_mutation
backbone_originInvitrogen
backbone_size5437
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
CUL2
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5BamHI
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneCUL2
id8453
genbank_ids
NM_003591
mutation
namecullin 2
shRNA_sequence
size2235
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmyc3
resistance markers :
593
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA