This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pDESTmycDICER
catalog :
19873
citations: 12
Reference
Lannom M, Nielsen J, Nawaz A, Shilikbay T, Ceman S. FMRP and MOV10 regulate Dicer1 expression and dendrite development. PLoS ONE. 2021;16:e0260005 pubmed publisher
Yang X, Wang X, Li Z, Duan S, Li H, Jin J, et al. An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation. Sci Adv. 2021;7:eabi6684 pubmed publisher
Zhang Y, Xu Y, Dai Y, Li Z, Wang J, Ye Z, et al. Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2. PLoS Pathog. 2021;17:e1009790 pubmed publisher
Zhang Y, Li Z, Ye Z, Xu Y, Wang B, Wang C, et al. The activation of antiviral RNA interference not only exists in neural progenitor cells but also in somatic cells in mammals. Emerg Microbes Infect. 2020;9:1580-1589 pubmed publisher
Paulsson J, Wang N, Gao J, Stenman A, Zedenius J, Mu N, et al. GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours. Endocr Relat Cancer. 2020;: pubmed publisher
Boudouresque F, Siret C, Dobric A, Silvy F, Soubeyran P, Iovanna J, et al. Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells. Oncotarget. 2018;9:35941-35961 pubmed publisher
Liao S, Fukunaga R. Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro. Methods Mol Biol. 2018;1680:101-121 pubmed publisher
Ceolotto G, Giannella A, Albiero M, Kuppusamy M, Radu C, Simioni P, et al. miR-30c-5p regulates macrophage-mediated inflammation and pro-atherosclerosis pathways. Cardiovasc Res. 2017;113:1627-1638 pubmed publisher
Wang X, Jiang F, Tong H, Ke J, Li Y, Zhang H, et al. Dicer1 dysfunction promotes stemness and aggression in endometrial carcinoma. Tumour Biol. 2017;39:1010428317695967 pubmed publisher
Li Y, Basavappa M, Lu J, Dong S, Cronkite D, Prior J, et al. Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells. Nat Microbiol. 2016;2:16250 pubmed publisher
Ungvari Z, Tucsek Z, Sosnowska D, Toth P, Gautam T, Podlutsky A, et al. Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2013;68:877-91 pubmed publisher
Landthaler M, Gaidatzis D, Rothballer A, Chen P, Soll S, Dinic L, et al. Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs. RNA. 2008;14:2580-96 pubmed publisher
product information
Catalog Number :
19873
Product Name :
pDESTmycDICER
article :
doi10.1261/rna.1351608
id2069
pubmed_id18978028
bacterial resistance :
Ampicillin
cloning :
backbonepDESTmyc
backbone_mutation
backbone_origin
backbone_size5862
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
The Dicer insert contains an N1660Y mutation.
origin :
37
pi :
alt_names
DCR1, Dicer, HERNA, KIAA0928
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5CMV
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDCR1, Dicer, Dicer1e, GLOW, HERNA, K12H4.8-LIKE, MNG1, RMSE2, aviD
geneDICER1
id23405
genbank_ids
NM_177438
mutation
namedicer 1, ribonuclease type III
shRNA_sequence
size5772
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
locationC terminal on insert
tagHis
resistance markers :
536
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA