This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Orai1 CFP
catalog :
19757
citations: 5
Reference
Cantonero C, Camello P, Salido G, Rosado J, Redondo P. TMEM97 facilitates the activation of SOCE by downregulating the association of cholesterol to Orai1 in MDA-MB-231 cells. Biochim Biophys Acta Mol Cell Biol Lipids. 2021;1866:158906 pubmed publisher
Cantonero C, Sanchez Collado J, Lopez J, Salido G, Rosado J, Redondo P. Arachidonic Acid Attenuates Cell Proliferation, Migration and Viability by a Mechanism Independent on Calcium Entry. Int J Mol Sci. 2020;21: pubmed publisher
Parry D, Holmes T, Gamper N, El Sayed W, Hettiarachchi N, Ahmed M, et al. A homozygous STIM1 mutation impairs store-operated calcium entry and natural killer cell effector function without clinical immunodeficiency. J Allergy Clin Immunol. 2016;137:955-7.e8 pubmed publisher
Jozsef L, Tashiro K, Kuo A, Park E, Skoura A, Albinsson S, et al. Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry. J Biol Chem. 2014;289:9380-95 pubmed publisher
Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A, Hogan P. Orai1 is an essential pore subunit of the CRAC channel. Nature. 2006;443:230-3 pubmed
product information
Catalog Number :
19757
Product Name :
Orai1 CFP
article :
doi10.1038/nature05122
id2324
pubmed_id16921383
bacterial resistance :
Kanamycin
cloning :
backboneEGFP-N1
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
ORAI calcium release-activated calcium modulator 1
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3EGFP-N
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCRACM1, IMD9, ORAT1, TAM2, TMEM142A
geneORAI1
id84876
genbank_ids
mutation
nameOrai1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagCFP
resistance markers :
410
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA