This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Flag- MCL1-3A (S159, S162, T163 mutated to A)
catalog :
197458
citations: 1
Reference
Keyan K, Alanany R, Kohil A, Khan O. E3 Ubiquitin Ligase TRIP12 Controls Exit from Mitosis via Positive Regulation of MCL-1 in Response to Taxol. Cancers (Basel). 2023;15: pubmed publisher
product information
Catalog Number :
197458
Product Name :
Flag- MCL1-3A (S159, S162, T163 mutated to A)
article :
doi10.3390/cancers15020505
id28233780
pubmed_id36672454
bacterial resistance :
Kanamycin
cloning :
backbonepCMV-Tag2A
backbone_mutation
backbone_originStratagene
backbone_size4300
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
MCL-1 phosphodegron mutants
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3ECOR1
cloning_site_5BAMH1
promoterCMV
sequencing_primer_3
sequencing_primer_5CMV Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
geneMCL1
id4170
genbank_ids
NM_021960
mutationS159A, S161A, T163A
nameMCL1
shRNA_sequence
size1100
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFlag
plasmid copy :
The original plasmid is from Roger Davies lab, obtained from Addgene. The mutations were done in Dr Khan's lab.
resistance markers :
6462
tags :
High Copy
terms :
Zeocin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA