This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
hBax S184A C3-EGFP
catalog :
19742
citations: 3
Reference
Kale J, Kutuk O, Brito G, Andrews T, Leber B, Letai A, et al. Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. EMBO Rep. 2018;19: pubmed publisher
Reid C, Boye S, Hauswirth W, Lipinski D. miRNA-mediated post-transcriptional silencing of transgenes leads to increased adeno-associated viral vector yield and targeting specificity. Gene Ther. 2017;24:462-469 pubmed publisher
Nechushtan A, Smith C, Hsu Y, Youle R. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 1999;18:2330-41 pubmed
product information
Catalog Number :
19742
Product Name :
hBax S184A C3-EGFP
article :
doi10.1093/emboj/18.9.2330
id2322
pubmed_id10228148
bacterial resistance :
Kanamycin
cloning :
backboneC3-EGFP
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
BCL2-associated X protein
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5N/A
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL2L4
geneBAX
id581
genbank_ids
NM_138761
mutationSerine 184 to Alanine
nameBax S184A
shRNA_sequence
size579
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
resistance markers :
604
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA