This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
hBax C3-EGFP
catalog :
19741
citations: 8
Reference
Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, et al. Intracellular FGF1 protects cells from apoptosis through direct interaction with p53. Cell Mol Life Sci. 2023;80:311 pubmed publisher
Liu T, Lam V, Thieme E, Sun D, Wang X, Xu F, et al. Pharmacologic Targeting of Mcl-1 Induces Mitochondrial Dysfunction and Apoptosis in B-Cell Lymphoma Cells in a TP53- and BAX-Dependent Manner. Clin Cancer Res. 2021;: pubmed publisher
Matreyek K, Stephany J, Chiasson M, Hasle N, Fowler D. An improved platform for functional assessment of large protein libraries in mammalian cells. Nucleic Acids Res. 2019;: pubmed publisher
Kale J, Kutuk O, Brito G, Andrews T, Leber B, Letai A, et al. Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. EMBO Rep. 2018;19: pubmed publisher
Rudd A, Devaraj N. Traceless synthesis of ceramides in living cells reveals saturation-dependent apoptotic effects. Proc Natl Acad Sci U S A. 2018;115:7485-7490 pubmed publisher
Mattiolo P, Barbero Farran A, Amigó J, Ripamonti M, Ribas J, Boix J. Cell death induced by 2-phenylethynesulfonamide uncovers a pro-survival function of BAX. Cancer Lett. 2014;354:115-21 pubmed publisher
Parrondo R, de las Pozas A, Reiner T, Perez Stable C. ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells. Peerj. 2013;1:e144 pubmed publisher
Nechushtan A, Smith C, Hsu Y, Youle R. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 1999;18:2330-41 pubmed
product information
Catalog Number :
19741
Product Name :
hBax C3-EGFP
article :
doi10.1093/emboj/18.9.2330
id2322
pubmed_id10228148
bacterial resistance :
Kanamycin
cloning :
backboneC3-EGFP
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
BCL2-associated X protein
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5N/A
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL2L4
geneBAX
id581
genbank_ids
NM_138761
mutationnone
nameBax
shRNA_sequence
size579
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
resistance markers :
604
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA