This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3 Flag MKK7B2Jnk1a1(APF)
catalog :
19730
citations: 11
Reference
Nordgaard C, Tollenaere M, Val A, Bekker Jensen D, Blasius M, Olsen J, et al. Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses. Int J Mol Sci. 2021;22: pubmed publisher
Yang J, Wang J, Liu Y, Zhang Y, Huang W, Zou Y, et al. PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation. Cell Death Dis. 2021;12:707 pubmed publisher
Chen C, Strouz K, Huang K, Shyu A. Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation. RNA. 2020;: pubmed publisher
Pein M, Insua Rodríguez J, Hongu T, Riedel A, Meier J, Wiedmann L, et al. Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs. Nat Commun. 2020;11:1494 pubmed publisher
Insua Rodríguez J, Pein M, Hongu T, Meier J, Descot A, Lowy C, et al. Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis. EMBO Mol Med. 2018;10: pubmed publisher
Kim E, Jung J, Kim A, Chang Y, Kim S. ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer. Neoplasia. 2017;19:354-363 pubmed publisher
Rui Y, Xu Z, Chen Z, Zhang S. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells. Autophagy. 2015;11:812-32 pubmed publisher
Jha A, Ahuja M, Patel S, Brailoiu E, Muallem S. Convergent regulation of the lysosomal two-pore channel-2 by Mg²?, NAADP, PI(3,5)P? and multiple protein kinases. EMBO J. 2014;33:501-11 pubmed publisher
Sun G, Irvine K. Ajuba family proteins link JNK to Hippo signaling. Sci Signal. 2013;6:ra81 pubmed publisher
Oehrl W, Cotsiki M, Panayotou G. Differential regulation of M3/6 (DUSP8) signaling complexes in response to arsenite-induced oxidative stress. Cell Signal. 2013;25:429-38 pubmed publisher
Lei K, Nimnual A, Zong W, Kennedy N, Flavell R, Thompson C, et al. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol. 2002;22:4929-42 pubmed
product information
Catalog Number :
19730
Product Name :
pCDNA3 Flag MKK7B2Jnk1a1(APF)
article :
doi10.1128/MCB.22.13.4929-4942.2002
id2319
pubmed_id12052897
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_origininvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
MAP2K7
JNK1
JNK
cloning
clone_methodRestriction Enzyme
cloning_site_3Hind III
cloning_site_5Hind III
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesJNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c
geneMAPK8
id5599
aliases5930412N11Rik, JNKK 2, Jnkk, Jnkk2, MAPKK 7, MEK 7, Mapkk7, Mek7, Mkk7, Prkm, Prkmk7, sek, sek2
geneMap2k7
id26400
genbank_ids
mutationreplaced dual phosporylation motif Thr(1959)-Pro-Tyr(1965) with Ala-Pro-Phe
nameMKK7B2Jnk1a1(APF)
shRNA_sequence
size2559
species
9606
Homo sapiens
10090
Mus musculus
tags
locationN terminal on insert
tagFlag
resistance markers :
106
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA