This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HA-HIF1alpha-wt-pBabe-puro
catalog :
19365
citations: 9
Reference
Masgras I, Cannino G, Ciscato F, Sanchez Martin C, Darvishi F, Scantamburlo F, et al. Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD+ and SIRT3. Cell Death Differ. 2022;: pubmed publisher
Zhang X, Sun Y, Cheng S, Yao Y, Hua X, Shi Y, et al. CDK6 increases glycolysis and suppresses autophagy by mTORC1-HK2 pathway activation in cervical cancer cells. Cell Cycle. 2022;21:984-1002 pubmed publisher
Sun Y, Lin X, Liu B, Zhang Y, Li W, Zhang S, et al. Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells. Sci Adv. 2021;7:eabj6877 pubmed publisher
Loveless T, Grotts J, Schechter M, Forouzmand E, Carlson C, Agahi B, et al. Lineage tracing and analog recording in mammalian cells by single-site DNA writing. Nat Chem Biol. 2021;17:739-747 pubmed publisher
Piasecka D, Braun M, Mieszkowska M, Kowalczyk L, Kopczynski J, Kordek R, et al. Upregulation of HIF1-α via an NF-κB/COX2 pathway confers proliferative dominance of HER2-negative ductal carcinoma in situ cells in response to inflammatory stimuli. Neoplasia. 2020;22:576-589 pubmed publisher
Tosatto A, Sommaggio R, Kummerow C, Bentham R, Blacker T, Berecz T, et al. The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α. EMBO Mol Med. 2016;8:569-85 pubmed publisher
Liu N, Xia W, Liu S, Chen H, Sun L, Liu M, et al. MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition. Sci Rep. 2016;6:20489 pubmed publisher
Trisciuoglio D, Gabellini C, Desideri M, Ziparo E, Zupi G, Del Bufalo D. Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90. PLoS ONE. 2010;5:e11772 pubmed publisher
Yan Q, Bartz S, Mao M, Li L, Kaelin W. The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol Cell Biol. 2007;27:2092-102 pubmed
product information
Catalog Number :
19365
Product Name :
HA-HIF1alpha-wt-pBabe-puro
article :
doi10.1128/MCB.01514-06
id2219
pubmed_id17220275
bacterial resistance :
Ampicillin
cloning :
backbonepBabe-puro
backbone_mutation
backbone_origin
backbone_size5188
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth temp :
DH5alpha
origin :
37
pi :
alt_names
HIF1a
cloning
clone_methodRestriction Enzyme
cloning_site_3Not I
cloning_site_5BamH I
promoter
sequencing_primer_3
sequencing_primer_5pBabe-5'
site_3_destroyed1
site_5_destroyed
entrez_gene
aliasesHIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
geneHIF1A
id3091
genbank_ids
NM_001530
mutationwt human cDNA
nameHypoxia inducible factor 1 alpha
shRNA_sequence
size2515
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA-tag
resistance markers :
238
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA