This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3 deltaN47 Beta-catenin
catalog :
19287
citations: 5
Reference
Kazi A, Xiang S, Yang H, Delitto D, Trevino J, Jiang R, et al. GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors. Nat Commun. 2018;9:5154 pubmed publisher
Alshareef A, Gupta N, Zhang H, Wu C, Haque M, Lai R. High expression of β-catenin contributes to the crizotinib resistant phenotype in the stem-like cell population in neuroblastoma. Sci Rep. 2017;7:16863 pubmed publisher
Long M, Lin H, Parvez S, Zhao Y, Poganik J, Huang P, et al. β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Cell Chem Biol. 2017;24:944-957.e7 pubmed publisher
Qu Y, Gharbi N, Yuan X, Olsen J, Blicher P, Dalhus B, et al. Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer. Proc Natl Acad Sci U S A. 2016;113:9339-44 pubmed publisher
Kolligs F, Hu G, Dang C, Fearon E. Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression. Mol Cell Biol. 1999;19:5696-706 pubmed
product information
Catalog Number :
19287
Product Name :
pcDNA3 deltaN47 Beta-catenin
article :
doi
id2057
pubmed_id10409758
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Has 12-bp sequence upstream of the initiating ATG codon matching the consensus Kozak initiator sequence.
origin :
37
pi :
alt_names
CTNNB1
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5BamHI
promoter
sequencing_primer_3BGH rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCTNNB, EVR7, MRD19, NEDSDV, armadillo
geneCTNNB1
id1499
genbank_ids
mutationN-terminal truncation, deleted aa 1-47
namebeta-catenin
shRNA_sequence
size2200
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFlag
resistance markers :
144
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA