This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV5 TBRI-HA with various GS domain mutations
catalog :
19162
citations: 4
Reference
Sun J, Tao R, Mao T, Feng Z, Guo Q, Zhang X. The involvement of lipid raft pathway in suppression of TGFβ-mediated metastasis by tolfenamic acid in hepatocellular carcinoma cells. Toxicol Appl Pharmacol. 2019;380:114696 pubmed publisher
Fujiwara T, Takeda N, Hara H, Morita H, Kishihara J, Inuzuka R, et al. Distinct variants affecting differential splicing of TGFBR1 exon 5 cause either Loeys-Dietz syndrome or multiple self-healing squamous epithelioma. Eur J Hum Genet. 2018;26:1151-1158 pubmed publisher
Huang Z, Li S, Fan W, Ma Q. Transforming growth factor β1 promotes invasion of human JEG-3 trophoblast cells via TGF-β/Smad3 signaling pathway. Oncotarget. 2017;8:33560-33570 pubmed publisher
Cichon M, Moruzzi M, Shqau T, Miller E, Mehner C, Ethier S, et al. MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer. Cancer Res. 2016;76:3520-30 pubmed publisher
product information
Catalog Number :
19162
Product Name :
pCMV5 TBRI-HA with various GS domain mutations
article :
doi
id1923
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepCMV5
backbone_mutation
backbone_origin
backbone_size4657
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
See author map for cloning details.
origin :
37
pi :
alt_names
TGFB1
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5CMV Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TBR-i, TBRI, TGFR-1, tbetaR-I
geneTGFBR1
id7046
genbank_ids
mutationT204D (GS domain mutation)
nametransforming growth factor, beta receptor 1
shRNA_sequence
size1700
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHA
plasmid copy :
R. Weiser
resistance markers :
313
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA