This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV5 TBRI-His
catalog :
19161
citations: 11
Reference
Nyati S, Gregg B, Xu J, Young G, Kimmel L, Nyati M, et al. TGFBR2 mediated phosphorylation of BUB1 at Ser-318 is required for transforming growth factor-β signaling. Neoplasia. 2020;22:163-178 pubmed publisher
Sun J, Tao R, Mao T, Feng Z, Guo Q, Zhang X. The involvement of lipid raft pathway in suppression of TGFβ-mediated metastasis by tolfenamic acid in hepatocellular carcinoma cells. Toxicol Appl Pharmacol. 2019;380:114696 pubmed publisher
Shih J, Lin H, Hsiao A, Su Y, Tsai S, Chien C, et al. Unveiling the role of microRNA-7 in linking TGF-β-Smad-mediated epithelial-mesenchymal transition with negative regulation of trophoblast invasion. FASEB J. 2019;33:6281-6295 pubmed publisher
Kim S, Ham S, Yang K, Kim K. Protein kinase CK2 activation is required for transforming growth factor β-induced epithelial-mesenchymal transition. Mol Oncol. 2018;12:1811-1826 pubmed publisher
Inoue Mochita M, Inoue T, Kojima S, Futakuchi A, Fujimoto T, Sato Ohira S, et al. Interleukin-6-mediated trans-signaling inhibits transforming growth factor-β signaling in trabecular meshwork cells. J Biol Chem. 2018;293:10975-10984 pubmed publisher
Gencer S, Oleinik N, Kim J, Panneer Selvam S, De Palma R, Dany M, et al. TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis. Sci Signal. 2017;10: pubmed publisher
Kim G, Lim H, Park H. Binding of coronin 1B to T?RI negatively regulates the TGF?1 signaling pathway. Biochem Biophys Res Commun. 2017;490:574-579 pubmed publisher
Gong H, An S, Sassmann A, Liu M, Mastej V, Mittal M, et al. PAR1 Scaffolds TGF?RII to Downregulate TGF-? Signaling and Activate ESC Differentiation to Endothelial Cells. Stem Cell Reports. 2016;7:1050-1058 pubmed publisher
Van Krieken R, Chen G, Gao B, Read J, Al Saleh H, Li R, et al. Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-? receptor I (T?RI) through exosomal secretion. Cell Signal. 2017;29:158-167 pubmed publisher
Nyati S, Chator A, Schinske K, Gregg B, Ross B, Rehemtulla A. A Requirement for ZAK Kinase Activity in Canonical TGF-? Signaling. Transl Oncol. 2016;9:473-481 pubmed publisher
Park B, Freeman Z, Ghasemzadeh A, Chattergoon M, Rutebemberwa A, Steigner J, et al. TGF?1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer. Cancer Discov. 2016;6:1366-1381 pubmed
product information
Catalog Number :
19161
Product Name :
pCMV5 TBRI-His
article :
doi
id1923
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepCMV5
backbone_mutation
backbone_origin
backbone_size4657
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
See author map for cloning details.
origin :
37
pi :
alt_names
TGFBR1
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5CMV Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TBR-i, TBRI, TGFR-1, tbetaR-I
geneTGFBR1
id7046
genbank_ids
mutation
nametransforming growth factor, beta receptor 1
shRNA_sequence
size1700
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHis
plasmid copy :
Rotrad
resistance markers :
313
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA