pGL2-Mcl-1 mut | Addgene 19133 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pGL2-Mcl-1 mut

catalog :

19133

citations: 2

Reference
Liu H, Yang J, Yuan Y, Xia Z, Chen M, Xie L, et al. Regulation of Mcl-1 by constitutive activation of NF-κB contributes to cell viability in human esophageal squamous cell carcinoma cells. BMC Cancer. 2014;14:98 pubmed publisher
Ricci M, Kim S, Ogi K, Plastaras J, Ling J, Wang W, et al. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell. 2007;12:66-80 pubmed

product information

Catalog Number :

19133

Product Name :

pGL2-Mcl-1 mut

article :

doi	10.1016/j.ccr.2007.05.006
id	2246
pubmed_id	17613437

bacterial resistance :

Ampicillin

cloning :

backbone

pGL2-basic

backbone_mutation

backbone_origin

backbone_size

5597

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Luciferase

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5	pGL2-Fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
gene	MCL1
id	4170

genbank_ids

mutation

NFkB binding-site mutant, the sequence GGGGTCTTCC in the NFkB-3 region was changed to GTTGTCTTCC.

name

Mcl-1 promoter

shRNA_sequence

size

325

species

9606

Homo sapiens