This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
shp63alpha pLKO.1 puro
catalog :
19120
citations: 4
Reference
Mendoza Rodríguez M, Ayala Sumuano J, Garcia Morales L, Zamudio Meza H, Pérez Yépez E, Meza I. IL-1β Inflammatory Cytokine-Induced TP63 Isoform ∆NP63α Signaling Cascade Contributes to Cisplatin Resistance in Human Breast Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
Chowdhury P, Lin G, Liu K, Song Y, Lin F, Lin W. Targeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapy. Nat Commun. 2014;5:5476 pubmed publisher
Arason A, Jónsdóttir H, Halldorsson S, Benediktsdóttir B, Bergthorsson J, Ingthorsson S, et al. deltaNp63 has a role in maintaining epithelial integrity in airway epithelium. PLoS ONE. 2014;9:e88683 pubmed publisher
Godar S, Ince T, Bell G, Feldser D, Donaher J, Bergh J, et al. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008;134:62-73 pubmed publisher
product information
Catalog Number :
19120
Product Name :
shp63alpha pLKO.1 puro
article :
doi10.1016/j.cell.2008.06.006
id2244
pubmed_id18614011
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1 puro
backbone_mutation
backbone_originGenHunter
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth notes :
shRNA against p63 (all isoforms), cloned by Watnick, RS. shRNA sequence - 5'-CCG GCC GTT TCG TCA GAA CAC ACA TCT CGA GAT GTG TGT TCT GAC GAA ACG GTT TTT
growth temp :
Use Stbl3 or HB101 to reduce chance of recombination.
origin :
37
pi :
alt_names
p63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p73H, p73L
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
geneTP63
id8626
genbank_ids
mutation
namesmall hairpin RNA against tumor protein p63
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
568
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA