This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFP C3-Lats1
catalog :
19053
citations: 6
Reference
Hennigan R, Thomson C, Stachowski K, Nassar N, Ratner N. Merlin tumor suppressor function is regulated by PIP2-mediated dimerization. PLoS ONE. 2023;18:e0281876 pubmed publisher
Wong D, Xiao J, Chew T, Pan M, Lee C, Ang J, et al. BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation. Adv Sci (Weinh). 2022;9:e2202834 pubmed publisher
Aureille J, Buffière Ribot V, Harvey B, Boyault C, Pernet L, Andersen T, et al. Nuclear envelope deformation controls cell cycle progression in response to mechanical force. EMBO Rep. 2019;20:e48084 pubmed publisher
Hennigan R, Fletcher J, Guard S, Ratner N. Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins. Sci Signal. 2019;12: pubmed publisher
Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura S, et al. Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells. Nat Commun. 2017;8:1246 pubmed publisher
Oka T, Mazack V, Sudol M. Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem. 2008;283:27534-46 pubmed publisher
product information
Catalog Number :
19053
Product Name :
pEGFP C3-Lats1
article :
doi10.1074/jbc.M804380200
id2226
pubmed_id18640976
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C3
backbone_mutation
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
** S1111L mutation is present in Lats1. It is not known whether this has any functional consequence.
origin :
37
pi :
alt_names
Lats1, N-mutant
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5N/A
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesWARTS, wts
geneLATS1
id9113
genbank_ids
NM_004690
mutation**
nameLarge tumor suppressor kinase 1, N mutant
shRNA_sequence
size3393
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagEGFP
resistance markers :
507
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA