delta-BRIP1-pcDNA3.1/MycHis | Addgene 19042 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

delta-BRIP1-pcDNA3.1/MycHis

catalog :

19042

citations: 1

Reference
De Nicolo A, Tancredi M, Lombardi G, Flemma C, Barbuti S, Di Cristofano C, et al. A novel breast cancer-associated BRIP1 (FANCJ/BACH1) germ-line mutation impairs protein stability and function. Clin Cancer Res. 2008;14:4672-80 pubmed publisher

product information

Catalog Number :

19042

Product Name :

delta-BRIP1-pcDNA3.1/MycHis

article :

doi	10.1158/1078-0432.CCR-08-0087
id	2241
pubmed_id	18628483

bacterial resistance :

Ampicillin

cloning :

backbone

pcDNA3.1

backbone_mutation

backbone_origin

Invitrogen

backbone_size

5493

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

origin :

pi :

alt_names

BRIP1

cloning

clone_method	Restriction Enzyme
cloning_site_3	Apa1
cloning_site_5	Not1
promoter
sequencing_primer_3	SP6
sequencing_primer_5	T7
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	BACH1, FANCJ, OF
gene	BRIP1
id	83990

aliases	BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53
gene	BRCA1
id	672

genbank_ids

AF360549

mutation

This is a novel BRIP1 germline mutation that consists of a 4-nucleotide deletion (c.2992-2995del AAGA) in BRIP1 exon 20. It causes a shift in the reading frame and disrupts the BRCA1-binding domain.

name

delta BRIP1

shRNA_sequence

size

species

9606

Homo sapiens