This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HA-HIF2alpha-P405A/P531A-pBabe-puro
catalog :
19006
citations: 5
Reference
Voss D, Spina R, Carter D, Lim K, Jeffery C, Bar E. Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression. Sci Rep. 2017;7:4292 pubmed publisher
Mathieu J, Zhou W, Xing Y, Sperber H, Ferreccio A, Agoston Z, et al. Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency. Cell Stem Cell. 2014;14:592-605 pubmed publisher
Emerling B, Benes C, Poulogiannis G, Bell E, Courtney K, Liu H, et al. Identification of CDCP1 as a hypoxia-inducible factor 2? (HIF-2?) target gene that is associated with survival in clear cell renal cell carcinoma patients. Proc Natl Acad Sci U S A. 2013;110:3483-8 pubmed publisher
Zhou W, Dosey T, Biechele T, Moon R, Horwitz M, Ruohola Baker H. Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct. PLoS ONE. 2011;6:e27460 pubmed publisher
Yan Q, Bartz S, Mao M, Li L, Kaelin W. The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol Cell Biol. 2007;27:2092-102 pubmed
product information
Catalog Number :
19006
Product Name :
HA-HIF2alpha-P405A/P531A-pBabe-puro
article :
doi10.1128/MCB.01514-06
id2219
pubmed_id17220275
bacterial resistance :
Ampicillin
cloning :
backbonepBabe-puro
backbone_mutation
backbone_origin
backbone_size5188
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth temp :
DH5alpha
origin :
37
pi :
alt_names
HIF2a
EPAS1
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoR I
cloning_site_5BamH I
promoter
sequencing_primer_3
sequencing_primer_5pBabe-5'
site_3_destroyed1
site_5_destroyed
entrez_gene
aliasesECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73
geneEPAS1
id2034
genbank_ids
HSU81984
mutationcDNA changed amino acids: P405A and P531A
nameHypoxia inducible factor 2 alpha
shRNA_sequence
size2643
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA-tag
resistance markers :
238
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA