This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Luciferase-pcDNA3
catalog :
18964
citations: 33
Reference
Kumar P, Kinger S, Dubey A, Jagtap Y, Choudhary A, Prasad A, et al. Trehalose Promotes Clearance of Proteotoxic Aggregation of Neurodegenerative Disease-Associated Aberrant Proteins. Mol Neurobiol. 2023;: pubmed publisher
Bolshette N, Ezagouri S, Dandavate V, Karavaeva I, Golik M, Wang H, et al. Carbon dioxide regulates cholesterol levels through SREBP2. PLoS Biol. 2023;21:e3002367 pubmed publisher
Jang S, Paek S, Kim J, Seong J, Lim W. A New Culture Model for Enhancing Estrogen Responsiveness in HR+ Breast Cancer Cells through Medium Replacement: Presumed Involvement of Autocrine Factors in Estrogen Resistance. Int J Mol Sci. 2023;24: pubmed publisher
Itakura S, Shohji A, Amagai S, Kitamura M, Takayama K, Sugibayashi K, et al. Gene knockdown in HaCaT cells by small interfering RNAs entrapped in grapefruit-derived extracellular vesicles using a microfluidic device. Sci Rep. 2023;13:3102 pubmed publisher
Dubey A, Mishra R, Jagtap Y, Kinger S, Kumar P, Dhiman R, et al. Itraconazole Confers Cytoprotection Against Neurodegenerative Disease-Associated Abnormal Protein Aggregation. Mol Neurobiol. 2023;60:2397-2412 pubmed publisher
Lal R, Moeller H, Thomson E, Horton T, Lee S, Freeman R, et al. Novel Pathogenic de novo INS p.T97P Variant Presenting with Severe Neonatal DKA. Endocrinology. 2021;: pubmed publisher
Pauli G, Chao P, Qin Z, Böttger R, Lee S, Li S. Liposomal Resiquimod for Enhanced Immunotherapy of Peritoneal Metastases of Colorectal Cancer. Pharmaceutics. 2021;13: pubmed publisher
Walters A, Santacana Font G, Li J, Routabi N, Qin Y, Claes N, et al. Nanoparticle-Mediated In Situ Molecular Reprogramming of Immune Checkpoint Interactions for Cancer Immunotherapy. ACS Nano. 2021;: pubmed publisher
Vaughan H, Zamboni C, Radant N, Bhardwaj P, Revai Lechtich E, Hassan L, et al. Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer. Mol Ther Oncolytics. 2021;21:377-388 pubmed publisher
Anderson C, Walton C, Shohet R. A Comparison of Focused and Unfocused Ultrasound for Microbubble-Mediated Gene Delivery. Ultrasound Med Biol. 2021;47:1785-1800 pubmed publisher
Ayad C, Libeau P, Lacroix Gimon C, Ladavière C, Verrier B. LipoParticles: Lipid-Coated PLA Nanoparticles Enhanced In Vitro mRNA Transfection Compared to Liposomes. Pharmaceutics. 2021;13: pubmed publisher
Aleshkina D, Iyyappan R, Lin C, Masek T, Pospisek M, Susor A. ncRNA BC1 influences translation in the oocyte. RNA Biol. 2021;:1-12 pubmed publisher
Sampey G, Iordanskiy S, Pleet M, DeMarino C, Romerio F, Mahieux R, et al. Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals. Viruses. 2020;12: pubmed publisher
Jaijyan D, Govindasamy K, Singh J, Bhattacharya S, Singh A. Establishment of a stable transfection method in Babesia microti and identification of a novel bidirectional promoter of Babesia microti. Sci Rep. 2020;10:15614 pubmed publisher
Mishra R, Amanullah A, Upadhyay A, Dhiman R, Dubey A, Singh S, et al. Ubiquitin ligase LRSAM1 suppresses neurodegenerative diseases linked aberrant proteins induced cell death. Int J Biochem Cell Biol. 2020;120:105697 pubmed publisher
Ashraf N, Sutton J, Yang Y, Ranxhi B, Libohova K, Shaw E, et al. Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia type 3 disease protein. Neurobiol Dis. 2019;:104697 pubmed publisher
García Olloqui P, Rodríguez Madoz J, Di Scala M, Abizanda G, Vales A, Olague C, et al. Effect of heart ischemia and administration route on biodistribution and transduction efficiency of AAV9 vectors. J Tissue Eng Regen Med. 2020;14:123-134 pubmed publisher
Yu X, Zhang Y, Wu B, Kurie J, Pertsemlidis A. The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5. Mol Ther Oncolytics. 2019;14:288-298 pubmed publisher
Li Y, Gong Y, Ning X, Peng D, Liu L, He S, et al. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J Exp Clin Cancer Res. 2018;37:276 pubmed publisher
Keszei M, Kritikou J, Sandfort D, He M, Oliveira M, Wurzer H, et al. Wiskott-Aldrich syndrome gene mutations modulate cancer susceptibility in the p53± murine model. Oncoimmunology. 2018;7:e1468954 pubmed publisher
Yu X, Zhang Y, Ma X, Pertsemlidis A. miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer. Cancer Lett. 2018;427:85-93 pubmed publisher
Sánchez Valdéz F, Padilla A, Wang W, Orr D, Tarleton R. Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure. elife. 2018;7: pubmed publisher
Yu X, Zhang Y, Cavazos D, Ma X, Zhao Z, Du L, et al. miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer. Cell Death Dis. 2018;9:193 pubmed publisher
Amanullah A, Mishra R, Upadhyay A, Reddy P, Das R, Mishra A. Indomethacin elicits proteasomal dysfunctions develops apoptosis through mitochondrial abnormalities. J Cell Physiol. 2018;233:1685-1699 pubmed publisher
Goubert E, Mircheva Y, Lasorsa F, Melon C, Profilo E, Sutera J, et al. Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation. Front Cell Neurosci. 2017;11:149 pubmed publisher
Jansova D, Koncicka M, Tetkova A, Cerna R, Malik R, Del Llano E, et al. Regulation of 4E-BP1 activity in the mammalian oocyte. Cell Cycle. 2017;16:927-939 pubmed publisher
Upadhyay A, Amanullah A, Mishra R, Kumar A, Mishra A. Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases. Mol Neurobiol. 2018;55:1169-1182 pubmed publisher
Upadhyay A, Amanullah A, Chhangani D, Joshi V, Mishra R, Mishra A. Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction. Mol Neurobiol. 2016;53:6968-6981 pubmed
Susor A, Jansova D, Cerna R, Danylevska A, Anger M, Toralova T, et al. Temporal and spatial regulation of translation in the mammalian oocyte via the mTOR-eIF4F pathway. Nat Commun. 2015;6:6078 pubmed publisher
Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Sci Rep. 2014;4:5077 pubmed publisher
Hosonaga M, Arima Y, Sugihara E, Kohno N, Saya H. Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells. Cancer Sci. 2014;105:779-87 pubmed publisher
Chhangani D, Mishra A. Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity. Sci Rep. 2013;3:1972 pubmed publisher
Safran M, Kim W, O Connell F, Flippin L, Gunzler V, Horner J, et al. Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production. Proc Natl Acad Sci U S A. 2006;103:105-10 pubmed
product information
Catalog Number :
18964
Product Name :
Luciferase-pcDNA3
article :
doi10.1073/pnas.0509459103
id2224
pubmed_id16373502
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5352
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth temp :
DH5alpha
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Xba I
cloning_site_5Hind III
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
genbank_ids
AAA89082
mutation
nameFirefly Luciferase
shRNA_sequence
size1689
species
derived from firefly and optimized for mamalian expression
tags
resistance markers :
238
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA