This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Cdc2-HA
catalog :
1888
citations: 6
Reference
Tang Z, Pilie P, Geng C, Manyam G, Yang G, Park S, et al. ATR Inhibition Induces CDK1-SPOP Signaling and Enhances Anti-PD-L1 Cytotoxicity in Prostate Cancer. Clin Cancer Res. 2021;: pubmed publisher
Horiuchi M, Kuga T, Saito Y, Nagano M, Adachi J, Tomonaga T, et al. The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1. J Biol Chem. 2018;293:15524-15537 pubmed publisher
Mazzolini L, Broban A, Froment C, Burlet Schiltz O, Besson A, Manenti S, et al. Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry. Cell Cycle. 2016;15:2742-52 pubmed publisher
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
Wu J, Kharebava G, Piao C, Stoica B, Dinizo M, Sabirzhanov B, et al. Inhibition of E2F1/CDK1 pathway attenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo. PLoS ONE. 2012;7:e42129 pubmed publisher
van den Heuvel S, Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science. 1993;262:2050-4 pubmed
product information
Catalog Number :
1888
Product Name :
Cdc2-HA
article :
doi10.1126/science.8266103
id114
pubmed_id8266103
bacterial resistance :
Ampicillin
cloning :
backbonepCMV-neo-Bam
backbone_mutation
backbone_origin
backbone_size6550
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
See scanned map.
origin :
37
pi :
alt_names
cell division cycle 2
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5BamHI
promoter
sequencing_primer_3Bglob-pA-R
sequencing_primer_5Bglob-intron-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCDC2, CDC28A, P34CDC2
geneCDK1
id983
genbank_ids
mutation
nameCdc2
shRNA_sequence
size945
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHA
resistance markers :
544
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA