This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
MSCV H-Ras V12 IRES GFP
catalog :
18780
citations: 10
Reference
Dykstra P, Rando T, Smolke C. Modulating myoblast differentiation with RNA-based controllers. PLoS ONE. 2022;17:e0275298 pubmed publisher
Zhang Y, Donaher J, Das S, Li X, Reinhardt F, Krall J, et al. Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis. Nat Cell Biol. 2022;24:554-564 pubmed publisher
Lopušná K, Nowialis P, Opavska J, Abraham A, Riva A, Opavsky R. Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling. EBioMedicine. 2021;63:103191 pubmed publisher
Zhang K, Myllymäki S, Gao P, Devarajan R, Kytölä V, Nykter M, et al. Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene. 2017;36:5681-5694 pubmed publisher
Keckesova Z, Donaher J, De Cock J, Freinkman E, Lingrell S, Bachovchin D, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543:681-686 pubmed publisher
Baisantry A, Bhayana S, Wrede C, Hegermann J, Haller H, Melk A, et al. The impact of autophagy on the development of senescence in primary tubular epithelial cells. Cell Cycle. 2016;15:2973-2979 pubmed
Chen B, Zheng B, DeRan M, Jarugumilli G, Fu J, Brooks Y, et al. ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity. Nat Chem Biol. 2016;12:686-93 pubmed publisher
Sung S, Choi J, Cheong H. Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras. Oncotarget. 2015;6:40405-17 pubmed publisher
Wang X, Lu H, Li T, Yu L, Liu G, Peng X, et al. Krüppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146a. Am J Cancer Res. 2013;3:356-73 pubmed
Galavotti S, Bartesaghi S, Faccenda D, Shaked Rabi M, Sanzone S, McEvoy A, et al. The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene. 2013;32:699-712 pubmed publisher
product information
Catalog Number :
18780
Product Name :
MSCV H-Ras V12 IRES GFP
article :
doi
id2161
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backboneMSCV-IRES-GFP
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
HRas V12
H-Ras
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5MSCV
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesC-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
geneHRAS
id3265
genbank_ids
NM_005343
mutationV12
nameH-Ras V12
shRNA_sequence
size526
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagIRES GFP
resistance markers :
301
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA