This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pWZL hygro H-Ras V12
catalog :
18749
citations: 15
Reference
Roh K, Noh J, Kim Y, Jang Y, Kim J, Choi H, et al. Lysosomal control of senescence and inflammation through cholesterol partitioning. Nat Metab. 2023;5:398-413 pubmed publisher
Meessen S, Najjar G, Azoitei A, Iben S, Bolenz C, Günes C. A Comparative Assessment of Replication Stress Markers in the Context of Telomerase. Cancers (Basel). 2022;14: pubmed publisher
Rao R, Han R, Ogurek S, Xue C, Wu L, Zhang L, et al. Glioblastoma Genetic Drivers Dictate the Function of Tumor-Associated Macrophages/Microglia and Responses to CSF1R Inhibition. Neuro Oncol. 2021;: pubmed publisher
Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin Y, et al. Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Nat Immunol. 2021;22:1219-1230 pubmed publisher
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, et al. ZNF768 links oncogenic RAS to cellular senescence. Nat Commun. 2021;12:4841 pubmed publisher
Kuzuoğlu Öztürk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang G, et al. Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Rep. 2021;35:109321 pubmed publisher
Marney C, Anderson E, Adnan M, Peng K, Hu Y, Weinhold N, et al. p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino. Cell Rep. 2021;35:109329 pubmed publisher
Schwartz M, Portugez A, Attia B, Tannenbaum M, Cohen L, Loza O, et al. Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation. Commun Biol. 2020;3:696 pubmed publisher
Zhao J, Tian X, Zhu Y, Zhang Z, Rydkina E, Yuan Y, et al. Reply to: Transformation of naked mole-rat cells. Nature. 2020;583:E8-E13 pubmed publisher
Mangialardi E, Chen K, Salmon B, Vacher J, Salmena L. Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts. Oncotarget. 2019;10:6378-6390 pubmed publisher
Njeru S, Kraus J, Meena J, Lechel A, Katz S, Kumar M, et al. Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor. Oncogene. 2019;: pubmed publisher
Masaldan S, Clatworthy S, Gamell C, Smith Z, Francis P, Denoyer D, et al. Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy. Redox Biol. 2018;16:322-331 pubmed publisher
Flanagan K, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur L, et al. c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors. Oncotarget. 2018;9:21-36 pubmed publisher
Gomez G, Volinia S, Croce C, Zanca C, Li M, Emnett R, et al. Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity. Cancer Res. 2014;74:1429-39 pubmed publisher
Serrano M, Lin A, McCurrach M, Beach D, Lowe S. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell. 1997;88:593-602 pubmed
product information
Catalog Number :
18749
Product Name :
pWZL hygro H-Ras V12
article :
doi10.1016/S0092-8674(00)81902-9
id2162
pubmed_id9054499
bacterial resistance :
Ampicillin
cloning :
backbonepWZL Hygro
backbone_mutation
backbone_originAvailable at Addgene (#18750)
backbone_size5915
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
HRas V12
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5pBABE 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesC-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
geneHRAS
id3265
genbank_ids
NM_005343
mutationV12
nameH-Ras V12
shRNA_sequence
size526
species
9606
Homo sapiens
tags
plasmid copy :
Jay Morgenstern
resistance markers :
301
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA