This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
mEGFP-HRas G12V
catalog :
18666
citations: 12
Reference
Stout A, Zhang X, Letcher S, Rittenberg M, Shub M, Chai K, et al. Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production. bioRxiv. 2023;: pubmed publisher
Tejeda Muñoz N, Morselli M, Moriyama Y, Sheladiya P, Pellegrini M, De Robertis E. Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis. iScience. 2022;25:104123 pubmed publisher
Tu X, Yasuda R, Colgan L. Rac1 is a downstream effector of PKCα in structural synaptic plasticity. Sci Rep. 2020;10:1777 pubmed publisher
Podkalicka J, Biernatowska A, Olszewska P, Tabaczar S, Sikorski A. The microdomain-organizing protein MPP1 is required for insulin-stimulated activation of H-Ras. Oncotarget. 2018;9:18410-18421 pubmed publisher
Kenyon A, Gavriouchkina D, Zorman J, Chong Morrison V, Napolitani G, Cerundolo V, et al. Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes. Dis Model Mech. 2018;11: pubmed publisher
Ng M, Wang M, Casey P, Gan Y, Hagen T. Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif). PLoS ONE. 2017;12:e0171464 pubmed publisher
Mattison S, Blatch G, Edkins A. HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature. Cell Stress Chaperones. 2017;22:213-223 pubmed publisher
Michael J, Wurtzel J, Goldfinger L. Inhibition of Galectin-1 Sensitizes HRAS-driven Tumor Growth to Rapamycin Treatment. Anticancer Res. 2016;36:5053-5061 pubmed
Michael J, Wurtzel J, Goldfinger L. Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains. Oncogenesis. 2016;5:e228 pubmed publisher
Frei D, Hodneland E, Rios Mondragon I, Burtey A, Neumann B, Bulkescher J, et al. Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer. Sci Rep. 2015;5:12879 pubmed publisher
Wurtzel J, Kumar P, Goldfinger L. Palmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading. Small Gtpases. 2012;3:139-53 pubmed publisher
Yasuda R, Harvey C, Zhong H, Sobczyk A, Van Aelst L, Svoboda K. Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging. Nat Neurosci. 2006;9:283-91 pubmed
product information
Catalog Number :
18666
Product Name :
mEGFP-HRas G12V
article :
doi10.1038/nn1635
id2126
pubmed_id16429133
bacterial resistance :
Ampicillin
cloning :
backbonepCI
backbone_mutation
backbone_originPromega
backbone_size4000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
HRas
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5CMV Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesC-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
geneHRAS
id3265
genbank_ids
mutationG12V mutation in HRas
nameH-Ras
shRNA_sequence
size600
species
9606
Homo sapiens
tags
locationN terminal on insert
tagmonomeric EGFP
resistance markers :
511
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA