Reference |
---|
Tarallo D, Mart xed nez J, Leyva A, M xf3 naco A, Perroni C, Tassano M, et al. Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy. Sci Rep. 2024;14:909 pubmed publisher
|
Tang Q, Sensale S, Bond C, Xing J, Qiao A, Hugelier S, et al. Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets. Curr Biol. 2023;33:5169-5184.e8 pubmed publisher
|
Taylor K, Piasecka A, Kajdasz A, Brz x119 k A, Polay Espinoza M, Bourgeois C, et al. Modulatory role of RNA helicases in MBNL-dependent alternative splicing regulation. Cell Mol Life Sci. 2023;80:335 pubmed publisher
|
Zhang W, Lu C, Nakamoto M, Tsai C, Roy A, Lee C, et al. Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions. Nat Cell Biol. 2023;25:1453-1464 pubmed publisher
|
Liu Y, Yu K, Kong X, Zhang K, Wang L, Zhang N, et al. FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer. Sci Adv. 2023;9:eadg7112 pubmed publisher
|
Wang L, Li G, Zhou Z, Ge C, Chen Q, Liu Y, et al. Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263. Oncogene. 2023;42:2329-2346 pubmed publisher
|
Varghese G, Patra D, Jaikumar V, Rajan A, Latha N, Srinivas P. βhCG mediates immune suppression through upregulation of CD11b+ Gr1+ myeloid derived suppressor cells, CD206+ M2 macrophages, and CD4+ FOXP3+ regulatory T-cells in BRCA1 deficient breast cancers. Immunology. 2023;: pubmed publisher
|
Shi F, de Fatima Silva F, Liu D, Patel H, Xu J, Zhang W, et al. Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning. Mol Metab. 2023;74:101753 pubmed publisher
|
Le Minh G, Esquea E, Dhameliya T, Merzy J, Lee M, Ball L, et al. Kruppel-like factor 8 regulates triple negative breast cancer stem cell-like activity. Front Oncol. 2023;13:1141834 pubmed publisher
|
Wang M, Wisniewski C, Xiong C, Chhoy P, Goel H, Kumar A, et al. Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer. Sci Transl Med. 2023;15:eade5855 pubmed publisher
|
Kurden Pekmezci A, Cakiroglu E, Eris S, Mazi F, Coskun Deniz O, Dalgic E, et al. MALT1 paracaspase is overexpressed in hepatocellular carcinoma and promotes cancer cell survival and growth. Life Sci. 2023;323:121690 pubmed publisher
|
Zhang W, Lu C, Nakamoto M, Tsai C, Roy A, Lee C, et al. Curved adhesions mediate cell attachment to soft matrix fibres in 3D. bioRxiv. 2023;: pubmed publisher
|
Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt J, et al. RHINO restricts MMEJ activity to mitosis. bioRxiv. 2023;: pubmed publisher
|
Shinohara T, Yamamoto T, Morimoto H, Shiromoto Y, Kanatsu Shinohara M. Allogeneic offspring produced by induction of PD-L1 in spermatogonial stem cells via self-renewal stimulation. Stem Cell Reports. 2023;18:985-998 pubmed publisher
|
Eshima H, Shahtout J, Siripoksup P, Pearson M, Mahmassani Z, Ferrara P, et al. Lipid hydroperoxides promote sarcopenia through carbonyl stress. elife. 2023;12: pubmed publisher
|
Lu Z, Hu Q, Qin Y, Yang H, Xiao B, Chen W, et al. SETD8 inhibits ferroptosis in pancreatic cancer by inhibiting the expression of RRAD. Cancer Cell Int. 2023;23:50 pubmed publisher
|
Miyazaki T, Kanatsu Shinohara M, Ogonuki N, Matoba S, Ogura A, Yabe Nishimura C, et al. Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro. Development. 2023;150: pubmed publisher
|
Couto Silva C, Nunes K, Venturini G, Ara xfa jo Castro E Silva M, Pereira L, Comas D, et al. Indigenous people from Amazon show genetic signatures of pathogen-driven selection. Sci Adv. 2023;9:eabo0234 pubmed publisher
|
Yang F, Kalantari S, Ruan B, Sun S, Bian Z, Guan J. Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling. Nat Commun. 2023;14:978 pubmed publisher
|
Miyazaki Y, Goto T, Li X, Nakayama K, Okasho K, Takeda M, et al. Up-regulation of secretory leukocyte protease inhibitor in human samples might have a potential role of predicting prostate cancer recurrence and progression after surgery and hormonal therapy. Cancer Med. 2023;12:3328-3342 pubmed publisher
|
Choi K, Ko C, An S, Cho S, Rowland D, Kim J, et al. Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT. Mol Metab. 2023;69:101679 pubmed publisher
|
Shmakova A, Popov V, Romanov I, Khabibullin N, Sabitova N, Karpukhina A, et al. Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19. Int J Mol Sci. 2023;24: pubmed publisher
|
Llaurado Fernandez M, Hijmans E, Gennissen A, Wong N, Li S, Wisman G, et al. NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition. Mol Cancer Ther. 2022;21:1862-1874 pubmed publisher
|
Kaur H, Moreau R. Raptor knockdown concurrently increases the electrical resistance and paracellular permeability of Caco-2 cell monolayers. Life Sci. 2022;308:120989 pubmed publisher
|
Razpotnik R, Vidmar R, Fonovi x107 M, Rozman D, Re x17e en T. Circular RNA hsa_circ_0062682 Binds to YBX1 and Promotes Oncogenesis in Hepatocellular Carcinoma. Cancers (Basel). 2022;14: pubmed publisher
|
Mello A, Ngodup T, Lee Y, Donahue K, Li J, Rao A, et al. Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer. Oncogenesis. 2022;11:56 pubmed publisher
|
Rios Garcia M, Meissburger B, Chan J, de Guia R, Mattijssen F, Roessler S, et al. Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2-Dependent Mitotic Cell Death. Adv Sci (Weinh). 2022;9:e2104291 pubmed publisher
|
Frey K, Goetze S, Rohrer L, von Eckardstein A, Wollscheid B. Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions. Int J Mol Sci. 2022;23: pubmed publisher
|
Liu H, Heller Trulli D, Moore C. Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal. iScience. 2022;25:104804 pubmed publisher
|
Park S, Shon D, Kim J, Ryu Y, Ko Y. SAMM50 Regulates Thermogenesis of Beige Adipocytes Differentiated from Human Adipose-Derived Stem Cells by Balancing Mitochondrial Dynamics. Int J Mol Sci. 2022;23: pubmed publisher
|
Diaz Valdivia N, Simón L, Diaz J, Martínez Meza S, Contreras P, Burgos Ravanal R, et al. Mitochondrial Dysfunction and the Glycolytic Switch Induced by Caveolin-1 Phosphorylation Promote Cancer Cell Migration, Invasion, and Metastasis. Cancers (Basel). 2022;14: pubmed publisher
|
He B, Wang Z, Moreau R. Chylomicron production is repressed by RPTOR knockdown, R-α-lipoic acid and 4-phenylbutyric acid in human enterocyte-like Caco-2 cells. J Nutr Biochem. 2022;108:109087 pubmed publisher
|
Serna R, Ramrakhiani A, Hernández J, Chen C, Nakagawa C, Machida T, et al. c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. iScience. 2022;25:104325 pubmed publisher
|
Hall A, Pohl S, Cammareri P, Aitken S, Younger N, Raponi M, et al. RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer. Nat Commun. 2022;13:2791 pubmed publisher
|
Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, et al. KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4. Cell Rep. 2022;39:110788 pubmed publisher
|
Vicente Acosta A, Gimenez Cassina A, Diaz Nido J, Loría F. The smoothened agonist SAG reduces mitochondrial dysfunction and neurotoxicity of frataxin-deficient astrocytes. J Neuroinflammation. 2022;19:93 pubmed publisher
|
Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, et al. BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents. Int J Mol Sci. 2022;23: pubmed publisher
|
Jeltema D, Wang J, Cai J, Kelley N, Yang Z, He Y. A Single Amino Acid Residue Defines the Difference in NLRP3 Inflammasome Activation between NEK7 and NEK6. J Immunol. 2022;208:2029-2036 pubmed publisher
|
Ayloo S, Lazo C, Sun S, Zhang W, Cui B, Gu C. Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier. Neuron. 2022;110:1641-1655.e6 pubmed publisher
|
Kummer D, Steinbacher T, Thölmann S, Schwietzer M, Hartmann C, Horenkamp S, et al. A JAM-A-tetraspanin-αvβ5 integrin complex regulates contact inhibition of locomotion. J Cell Biol. 2022;221: pubmed publisher
|
Florian A, Woodley C, Wang J, Grieb B, Slota M, Guerrazzi K, et al. Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells. NAR Cancer. 2022;4:zcac007 pubmed publisher
|
Wang Y, Bao G, Zhang M, Xiang J, Zhou H, Wahafu A, et al. CRB2 enhances malignancy of glioblastoma via activation of the NF-κB pathway. Exp Cell Res. 2022;414:113077 pubmed publisher
|
Chen H, Yu Y, Yang M, Huang H, Ma S, Hu J, et al. YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner. Cell Biosci. 2022;12:19 pubmed publisher
|
Kim M, Jeong H, Krainc D. Lysosomal ceramides regulate Cathepsin B-mediated processing of saposin C and glucocerebrosidase activity. Hum Mol Genet. 2022;: pubmed publisher
|
Kim H, Jang S, Lee Y. The m6A(m)-independent role of FTO in regulating WNT signaling pathways. Life Sci Alliance. 2022;5: pubmed publisher
|
Li Y, Zhu Y, Feng S, Ishida Y, Chiu T, Saito T, et al. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep. 2022;38:110284 pubmed publisher
|
Martin M, Sandhu P, Kumar R, Buchkovich N. The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels. J Virol. 2022;96:e0180621 pubmed publisher
|
Zhao J, Dong Y, Chen X, Xiao X, Tan B, Chen G, et al. p53 Inhibition Protects against Neuronal Ischemia/Reperfusion Injury by the p53/PRAS40/mTOR Pathway. Oxid Med Cell Longev. 2021;2021:4729465 pubmed publisher
|
Abokyi S, Shan S, Lam C, Catral K, Pan F, Chan H, et al. Targeting Lysosomes to Reverse Hydroquinone-Induced Autophagy Defects and Oxidative Damage in Human Retinal Pigment Epithelial Cells. Int J Mol Sci. 2021;22: pubmed publisher
|
Taylor S, Ramsamooj S, Liang R, Katti A, Pozovskiy R, VASAN N, et al. Dietary fructose improves intestinal cell survival and nutrient absorption. Nature. 2021;597:263-267 pubmed publisher
|
Quadri R, Sertic S, Ghilardi A, Rondelli D, Gallo G, Del Giacco L, et al. Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation. Int J Mol Sci. 2021;22: pubmed publisher
|
Lee B, Boyer J, Burnett G, Thottumkara A, Tibrewal N, Wilson S, et al. Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth. Nat Chem Biol. 2021;: pubmed publisher
|
Huang N, Li S, Xie Y, Han Q, Xu X, Sheng Z. Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia. Curr Biol. 2021;31:3098-3114.e7 pubmed publisher
|
Conlon M, Poltorack C, Forcina G, Armenta D, Mallais M, Perez M, et al. A compendium of kinetic modulatory profiles identifies ferroptosis regulators. Nat Chem Biol. 2021;17:665-674 pubmed publisher
|
Arenas E, Martínez Sabadell A, Rius Ruiz I, Román Alonso M, Escorihuela M, Luque A, et al. Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation. Nat Commun. 2021;12:1237 pubmed publisher
|
Uneda A, Kurozumi K, Fujimura A, Fujii K, Ishida J, Shimazu Y, et al. Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration. Acta Neuropathol Commun. 2021;9:29 pubmed publisher
|
Muendlein H, Connolly W, Magri Z, Smirnova I, Ilyukha V, Gautam A, et al. ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1. Nat Commun. 2021;12:86 pubmed publisher
|
Kaur H, Moreau R. Curcumin represses mTORC1 signaling in Caco-2 cells by a two-sided mechanism involving the loss of IRS-1 and activation of AMPK. Cell Signal. 2021;78:109842 pubmed publisher
|
Kaur H, Moreau R. Curcumin steers THP-1 cells under LPS and mTORC1 challenges toward phenotypically resting, low cytokine-producing macrophages. J Nutr Biochem. 2021;88:108553 pubmed publisher
|
Duan Y, Zhang L, Angosto Bazarra D, Pelegrin P, Nunez G, He Y. RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly. Cell Rep. 2020;33:108405 pubmed publisher
|
Dean J, He A, Tan M, Wang J, Lu D, Razani B, et al. MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression. Cell Rep. 2020;33:108228 pubmed publisher
|
Fujimura A, Yasui S, Igawa K, Ueda A, Watanabe K, Hanafusa T, et al. In Vitro Studies to Define the Cell-Surface and Intracellular Targets of Polyarginine-Conjugated Sodium Borocaptate as a Potential Delivery Agent for Boron Neutron Capture Therapy. Cells. 2020;9: pubmed publisher
|
Zhan H, Bhattacharya S, Cai H, Iglesias P, Huang C, Devreotes P. An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells. Dev Cell. 2020;54:608-623.e5 pubmed publisher
|
Brownmiller T, Juric J, Ivey A, Harvey B, Westemeier E, Winters M, et al. Y Chromosome LncRNA are involved in Radiation Response of Male Non-Small Cell Lung Cancer Cells. Cancer Res. 2020;: pubmed publisher
|
Sobral L, Sechler M, Parrish J, McCann T, Jones K, Black J, et al. KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma. Genes Cancer. 2020;11:53-65 pubmed publisher
|
Ho K, Yang X, Osipovich A, Cabrera O, Hayashi M, Magnuson M, et al. Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion Via Tau Phosphorylation. Diabetes. 2020;: pubmed publisher
|
Wang S, Liu J, Qin J, Zhu Y, Tin V, Yam J, et al. CAMK2A supported tumor initiating cells of lung adenocarcinoma by upregulating SOX2 through EZH2 phosphorylation. Cell Death Dis. 2020;11:410 pubmed publisher
|
Dan X, Babbar M, Moore A, Wechter N, Tian J, Mohanty J, et al. DNA damage invokes mitophagy through a pathway involving Spata18. Nucleic Acids Res. 2020;48:6611-6623 pubmed publisher
|
Nagaki Y, Motoyama S, Yamaguchi T, Hoshizaki M, Sato Y, Sato T, et al. m6 A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis. Genes Cells. 2020;: pubmed publisher
|
Bare D, Cherny V, DeCoursey T, Abukhdeir A, Morgan D. Expression and function of voltage gated proton channels (Hv1) in MDA-MB-231 cells. PLoS ONE. 2020;15:e0227522 pubmed publisher
|
Sun Q, Fan G, Zhuo Q, Dai W, Ye Z, Ji S, et al. Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop. Cell Prolif. 2020;53:e12816 pubmed publisher
|
Martello A, Lauriola A, Mellis D, Parish E, Dawson J, Imrie L, et al. Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy. EMBO Rep. 2020;21:e48192 pubmed publisher
|
Yang F, Sun S, Wang C, Haas M, Yeo S, Guan J. Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation. Br J Cancer. 2020;122:1791-1802 pubmed publisher
|
Zhou B, Chen T, Jiang Y, Wei X, Lu C, Li J, et al. Scinderin suppresses cell proliferation and predicts the poor prognosis of hepatocellular carcinoma. Oncol Lett. 2020;19:2011-2020 pubmed publisher
|
Yamamoto S, Lee S, Matsuzaki H, Kumagai Takei N, Yoshitome K, Sada N, et al. Enhanced expression of nicotinamide nucleotide transhydrogenase (NNT) and its role in a human T cell line continuously exposed to asbestos. Environ Int. 2020;138:105654 pubmed publisher
|
Smolina N, Khudiakov A, Knyazeva A, Zlotina A, Sukhareva K, Kondratov K, et al. Desmin mutations result in mitochondrial dysfunction regardless of their aggregation properties. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165745 pubmed publisher
|
Bryan A, Wang J, Howard G, Guarnaccia A, Woodley C, Aho E, et al. WDR5 is a conserved regulator of protein synthesis gene expression. Nucleic Acids Res. 2020;48:2924-2941 pubmed publisher
|
Ashcroft S, Bass J, Kazi A, Atherton P, Philp A. The vitamin D receptor regulates mitochondrial function in C2C12 myoblasts. Am J Physiol Cell Physiol. 2020;318:C536-C541 pubmed publisher
|
Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
|
Ma L, Cao Y, Hu J, Chu M. Casein kinase 2 interacting protein 1 positively regulates caudal-related homeobox 1 in intestinal-type gastric cancer. Chin Med J (Engl). 2020;133:154-164 pubmed publisher
|
Llorens M, Rossi F, García I, Cooke M, Abba M, Lopez Haber C, et al. PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1. Front Oncol. 2019;9:1323 pubmed publisher
|
Hu R, Lu Z. Long non‑coding RNA HCP5 promotes prostate cancer cell proliferation by acting as the sponge of miR‑4656 to modulate CEMIP expression. Oncol Rep. 2019;: pubmed publisher
|
Qin F, Shi X, Li H. Knockdown of Chimeric RNA by RNAi. Methods Mol Biol. 2020;2079:143-154 pubmed publisher
|
Kang Y, Han S, Jeon H, Lee S, Lee J, Yoo S, et al. Nogo receptor-vimentin interaction: a novel mechanism for the invasive activity of glioblastoma multiforme. Exp Mol Med. 2019;51:125 pubmed publisher
|
Park H, Lee S, Lee J, Shin H, Yoo S, Lee M, et al. Suppression of CD81 promotes bladder cancer cell invasion through increased matrix metalloproteinase expression via extracellular signal-regulated kinase phosphorylation. Investig Clin Urol. 2019;60:396-404 pubmed publisher
|
Yang L, Ning Z, Wang L, Yan X, Meng Z. HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma. Am J Cancer Res. 2019;9:1607-1621 pubmed
|
Lu P, Hogan Cann A, Kamboj A, Roy Chowdhury S, Aghanoori M, Fernyhough P, et al. Poly(ADP-ribose) polymerase-1 inhibits mitochondrial respiration by suppressing PGC-1α activity in neurons. Neuropharmacology. 2019;160:107755 pubmed publisher
|
Milenkovic V, Slim D, Bader S, Koch V, Heinl E, Alvarez Carbonell D, et al. CRISPR-Cas9 Mediated TSPO Gene Knockout alters Respiration and Cellular Metabolism in Human Primary Microglia Cells. Int J Mol Sci. 2019;20: pubmed publisher
|
Stone N, Gifford C, Thomas R, Pratt K, Samse Knapp K, Mohamed T, et al. Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 2019;25:87-102.e9 pubmed publisher
|
Wang W, Ishibashi J, Trefely S, Shao M, Cowan A, Sakers A, et al. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metab. 2019;: pubmed publisher
|
Fuentes Villalobos F, Farkas C, Riquelme Barrios S, Armijo M, Soto Rifo R, Pincheira R, et al. DISC1 promotes translation maintenance during sodium arsenite-induced oxidative stress. Biochim Biophys Acta Gene Regul Mech. 2019;1862:657-669 pubmed publisher
|
Hou X, Khan M, Turmaine M, Thrasivoulou C, Becker D, Ahmed A. Wnt signaling regulates cytosolic translocation of Connexin 43. Am J Physiol Regul Integr Comp Physiol. 2019;: pubmed publisher
|
Qin Y, Hu Q, Xu J, Ji S, Dai W, Liu W, et al. PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis. Cell Commun Signal. 2019;17:30 pubmed publisher
|
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, et al. Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. elife. 2019;8: pubmed publisher
|
Salvador Moreno N, Liu J, Haas K, Parker L, Chakraborty C, Kron S, et al. The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair. Nucleic Acids Res. 2019;47:2703-2715 pubmed publisher
|
Wang H, Wang X, Zhang K, Wang Q, Cao X, Wang Z, et al. Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration. Sci Adv. 2019;5:eaav4971 pubmed publisher
|
Bajc Česnik A, Darovic S, Prpar Mihevc S, Stalekar M, Malnar M, Motaln H, et al. Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies. J Cell Sci. 2019;132: pubmed publisher
|
Wang C, Tanjaya J, Shen J, Lee S, Bisht B, Pan H, et al. Peroxisome Proliferator-Activated Receptor-γ Knockdown Impairs Bone Morphogenetic Protein-2-Induced Critical-Size Bone Defect Repair. Am J Pathol. 2019;189:648-664 pubmed publisher
|
Bruns I, Sauer B, Burger M, Eriksson J, Hofmann U, Braun Y, et al. Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells. J Biol Chem. 2019;294:3037-3050 pubmed publisher
|
Anderson E, Ghamari Langroudi M, Cakir I, Litt M, Chen V, Reggiardo R, et al. Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. J Neuroendocrinol. 2019;31:e12670 pubmed publisher
|
OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, et al. A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV. elife. 2018;7: pubmed publisher
|
Kim D, Reyes Ordoñez A, Chen J. Lentivirus-Mediated RNAi in Skeletal Myogenesis. Methods Mol Biol. 2019;1889:95-110 pubmed publisher
|
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa E, Almada L, Mahurkar Joshi S, et al. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. 2019;68:1271-1286 pubmed publisher
|
Kim H, Kim D, Bae S, Gwak H, Jeon J, Kim J, et al. Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness. Exp Mol Med. 2018;50:137 pubmed publisher
|
Duan L, Perez R, Maki C. Alpha ketoglutarate levels, regulated by p53 and OGDH, determine autophagy and cell fate/apoptosis in response to Nutlin-3a. Cancer Biol Ther. 2018;:1-9 pubmed publisher
|
Chen B, Zhang Y, Yang Y, Chen S, Xu A, Wu L, et al. Involvement of telomerase activity inhibition and telomere dysfunction in silver nanoparticles anticancer effects. Nanomedicine (Lond). 2018;13:2067-2082 pubmed publisher
|
Feehan R, Nelson A, Shantz L. Inhibition of mTORC2 enhances UVB-induced apoptosis in keratinocytes through a mechanism dependent on the FOXO3a transcriptional target NOXA but independent of TRAIL. Cell Signal. 2018;52:35-47 pubmed publisher
|
Khan S, LaCroix M, Boyle G, Sherman M, Brown J, Amar F, et al. Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons. Acta Neuropathol. 2018;136:589-605 pubmed publisher
|
Messenger S, Woo S, Sun Z, Martin T. A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4. J Cell Biol. 2018;217:2877-2890 pubmed publisher
|
El Badawy A, Ghoneim N, Nasr M, Elkhenany H, Ahmed T, Ahmed S, et al. Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells. Biol Open. 2018;7: pubmed publisher
|
Williams E, Glauser L, Tsika E, Jiang H, Islam S, Moore D. Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting. Hum Mol Genet. 2018;27:3189-3205 pubmed publisher
|
Hojo N, Huisken A, Wang H, Chirshev E, Kim N, Nguyen S, et al. Snail knockdown reverses stemness and inhibits tumour growth in ovarian cancer. Sci Rep. 2018;8:8704 pubmed publisher
|
Robeson A, Lindblom K, Wojton J, Kornbluth S, Matsuura K. Dimer-specific immunoprecipitation of active caspase-2 identifies TRAF proteins as novel activators. EMBO J. 2018;37: pubmed publisher
|
Kaur H, He B, Zhang C, Rodriguez E, Hage D, Moreau R. Piperine potentiates curcumin-mediated repression of mTORC1 signaling in human intestinal epithelial cells: implications for the inhibition of protein synthesis and TNF? signaling. J Nutr Biochem. 2018;57:276-286 pubmed publisher
|
Berns K, Caumanns J, Hijmans E, Gennissen A, Severson T, Evers B, et al. ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors. Oncogene. 2018;37:4611-4625 pubmed publisher
|
Jenkins C, Gusscott S, Wong R, Shevchuk O, Rana G, Giambra V, et al. RUNX1 promotes cell growth in human T-cell acute lymphoblastic leukemia by transcriptional regulation of key target genes. Exp Hematol. 2018;64:84-96 pubmed publisher
|
Chan K, Wong O, Wong E, Chan K, Ip P, Tse K, et al. Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma. Int J Cancer. 2018;143:1456-1469 pubmed publisher
|
Wei C, Lin H, Cui S. The Forkhead Transcription Factor FOXC2 Is Required for Maintaining Murine Spermatogonial Stem Cells. Stem Cells Dev. 2018;27:624-636 pubmed publisher
|
Wang P, Xie R, Cheng M, Sapolsky R, Ji X, Zhao H. The mTOR cell signaling pathway is crucial to the long-term protective effects of ischemic postconditioning against stroke. Neurosci Lett. 2018;676:58-65 pubmed publisher
|
Han S, Pang M, Nelson C. Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. J Cell Sci. 2018;131: pubmed publisher
|
Pappas B, Yang Y, Wang Y, Kim K, Chung H, Cheung M, et al. p23 protects the human aryl hydrocarbon receptor from degradation via a heat shock protein 90-independent mechanism. Biochem Pharmacol. 2018;152:34-44 pubmed publisher
|
Huang J, Kim D, Shan J, Abu Arish A, Luo Y, Hanrahan J. Most bicarbonate secretion by Calu-3 cells is mediated by CFTR and independent of pendrin. Physiol Rep. 2018;6: pubmed publisher
|
Lee M, Lee J, Lee S, Yoo S, Kim J, Kim W, et al. Clinical, prognostic, and therapeutic significance of heat shock protein 27 in bladder cancer. Oncotarget. 2018;9:7961-7974 pubmed publisher
|
Creus Muncunill J, Rue L, Alcalá Vida R, Badillos Rodríguez R, Romaní Aumedes J, Marco S, et al. Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration. Mol Neurobiol. 2018;55:7728-7742 pubmed publisher
|
Sampson N, Brunner E, Weber A, Puhr M, Schafer G, Szyndralewiez C, et al. Inhibition of Nox4-dependent ROS signaling attenuates prostate fibroblast activation and abrogates stromal-mediated protumorigenic interactions. Int J Cancer. 2018;143:383-395 pubmed publisher
|
Qi Z, Xu H, Zhang S, Xu J, Li S, Gao H, et al. RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling. Int J Oncol. 2018;52:1105-1116 pubmed publisher
|
Xiong J, Kawagishi H, Yan Y, Liu J, Wells Q, Edmunds L, et al. A Metabolic Basis for Endothelial-to-Mesenchymal Transition. Mol Cell. 2018;69:689-698.e7 pubmed publisher
|
Liu R, Zhang T, Zhu G, Xing M. Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer. Nat Commun. 2018;9:579 pubmed publisher
|
Roilo M, Kullmann M, Hengst L. Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1. Nucleic Acids Res. 2018;46:3198-3210 pubmed publisher
|
Bollaert E, Johanns M, Herinckx G, de Rocca Serra A, Vandewalle V, Havelange V, et al. HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation. Cell Signal. 2018;44:158-170 pubmed publisher
|
Zhang Y, Zhu T, Liu J, Liu J, Gao D, Su T, et al. FLNa negatively regulated proliferation and metastasis in lung adenocarcinoma A549 cells via suppression of EGFR. Acta Biochim Biophys Sin (Shanghai). 2018;50:164-170 pubmed publisher
|
Jeon H, Yoo S, Choi H, Mun J, Kang H, Lee J, et al. Extracellular vesicles from KSHV-infected endothelial cells activate the complement system. Oncotarget. 2017;8:99841-99860 pubmed publisher
|
De Dominici M, Porazzi P, Soliera A, Mariani S, Addya S, Fortina P, et al. Targeting CDK6 and BCL2 Exploits the "MYB Addiction" of Ph+ Acute Lymphoblastic Leukemia. Cancer Res. 2018;78:1097-1109 pubmed publisher
|
Jafferali M, Figueroa R, Hasan M, Hallberg E. Spindle associated membrane protein 1 (Samp1) is required for the differentiation of muscle cells. Sci Rep. 2017;7:16655 pubmed publisher
|
Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
|
Gagliardi P, Somale D, Puliafito A, Chiaverina G, di Blasio L, Oneto M, et al. MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion. J Cell Biol. 2018;217:231-249 pubmed publisher
|
Shukla S, Cyrta J, Murphy D, Walczak E, Ran L, Agrawal P, et al. Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer Cell. 2017;32:792-806.e7 pubmed publisher
|
Mendoza P, SILVA P, Diaz J, Arriagada C, Canales J, Cerda O, et al. Calpain2 mediates Rab5-driven focal adhesion disassembly and cell migration. Cell Adh Migr. 2018;12:185-194 pubmed publisher
|
Jayatilaka H, Giri A, Karl M, Aifuwa I, Trenton N, Phillip J, et al. EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration. FASEB J. 2018;32:1207-1221 pubmed publisher
|
Venkataramani V, Küffer S, Cheung K, Jiang X, Trumper L, Wulf G, et al. CD31 Expression Determines Redox Status and Chemoresistance in Human Angiosarcomas. Clin Cancer Res. 2018;24:460-473 pubmed publisher
|
Kim J, Kim Y, Stinski M, Ahn J, Song Y. Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction. Front Microbiol. 2017;8:1854 pubmed publisher
|
Thiepold A, Lorenz N, Foltyn M, Engel A, Divé I, Urban H, et al. Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death. Brain. 2017;140:2623-2638 pubmed publisher
|
Arnoult N, Correia A, Ma J, Merlo A, Garcia Gomez S, Maric M, et al. Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN. Nature. 2017;549:548-552 pubmed publisher
|
Vu L, Pickering B, Cheng Y, Zaccara S, Nguyen D, Minuesa G, et al. The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017;23:1369-1376 pubmed publisher
|
Wong K, Liu J, Chan K. KIF7 attenuates prostate tumor growth through LKB1-mediated AKT inhibition. Oncotarget. 2017;8:54558-54571 pubmed publisher
|
Godse N, Khan N, Yochum Z, Gomez Casal R, Kemp C, Shiwarski D, et al. TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression. Clin Cancer Res. 2017;23:7324-7332 pubmed publisher
|
Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed publisher
|
Bindels L, Porporato P, Ducastel S, Sboarina M, Neyrinck A, Dewulf E, et al. Ffar2 expression regulates leukaemic cell growth in vivo. Br J Cancer. 2017;117:1336-1340 pubmed publisher
|
Lee D, Yu E, Ham I, Hur H, Kim Y. AKT inhibition is an effective treatment strategy in ARID1A-deficient gastric cancer cells. Onco Targets Ther. 2017;10:4153-4159 pubmed publisher
|
Kwun H, Wendzicki J, Shuda Y, Moore P, Chang Y. Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting. Oncogene. 2017;36:6784-6792 pubmed publisher
|
Gallagher L, Radhi O, Abdullah M, McCluskey A, Boyd M, Chan E. Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell Death Dis. 2017;8:e3014 pubmed publisher
|
Hertig V, Matos Nieves A, Garg V, Villeneuve L, Mamarbachi M, Caland L, et al. Nestin expression is dynamically regulated in cardiomyocytes during embryogenesis. J Cell Physiol. 2018;233:3218-3229 pubmed publisher
|
Kriebs A, Jordan S, Soto E, Henriksson E, Sandate C, Vaughan M, et al. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proc Natl Acad Sci U S A. 2017;114:8776-8781 pubmed publisher
|
Guo Y, Cui J, Ji Z, Cheng C, Zhang K, Zhang C, et al. miR-302/367/LATS2/YAP pathway is essential for prostate tumor-propagating cells and promotes the development of castration resistance. Oncogene. 2017;36:6336-6347 pubmed publisher
|
Button R, Roberts S, Willis T, Hanemann C, Luo S. Accumulation of autophagosomes confers cytotoxicity. J Biol Chem. 2017;292:13599-13614 pubmed publisher
|
Binothman N, Hachim I, Lebrun J, Ali S. CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target: Role of CPSF6 in Breast Cancer. EBioMedicine. 2017;21:65-78 pubmed publisher
|
Gu Y, Albuquerque C, Braas D, Zhang W, Villa G, Bi J, et al. mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Mol Cell. 2017;67:128-138.e7 pubmed publisher
|
Gatliff J, East D, Singh A, Alvarez M, Frison M, Matic I, et al. A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling. Cell Death Dis. 2017;8:e2896 pubmed publisher
|
Kraus R, Yu X, Cordes B, Sathiamoorthi S, Iempridee T, Nawandar D, et al. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PLoS Pathog. 2017;13:e1006404 pubmed publisher
|
Ahsan M, Tchernychev B, Kessler M, Solinga R, Arthur D, Linde C, et al. Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine. Physiol Rep. 2017;5: pubmed publisher
|
Chatterjee S, Huang E, Christie I, Burns T. Reactivation of the p90RSK-CDC25C Pathway Leads to Bypass of the Ganetespib-Induced G2-M Arrest and Mediates Acquired Resistance to Ganetespib in KRAS-Mutant NSCLC. Mol Cancer Ther. 2017;16:1658-1668 pubmed publisher
|
Moore C, Parrish J, Jedlicka P. MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth. PLoS ONE. 2017;12:e0178028 pubmed publisher
|
Nam M, Akie T, Sanosaka M, Craige S, Kant S, Keaney J, et al. Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression. Sci Rep. 2017;7:2013 pubmed publisher
|
Wald J, Hatakeyama J, Printsev I, Cuevas A, Fry W, Saldana M, et al. Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination. Oncogene. 2017;36:5158-5167 pubmed publisher
|
Lupey Green L, Moquin S, Martin K, McDevitt S, Hulse M, Caruso L, et al. PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoter. Virology. 2017;507:220-230 pubmed publisher
|
Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed publisher
|
Chan K, Matchett K, Coulter J, Yuen H, McCrudden C, Zhang S, et al. Erythropoietin drives breast cancer progression by activation of its receptor EPOR. Oncotarget. 2017;8:38251-38263 pubmed publisher
|
Gordon C, Gong X, Ganesh D, Brooks J. NUSAP1 promotes invasion and metastasis of prostate cancer. Oncotarget. 2017;8:29935-29950 pubmed publisher
|
Qu N, Hu J, Liu L, Zhang T, Sun G, Shi R, et al. SIRT6 is upregulated and associated with cancer aggressiveness in papillary thyroid cancer via BRAF/ERK/Mcl‑1 pathway. Int J Oncol. 2017;50:1683-1692 pubmed publisher
|
Sheu S, Chen J, Bee Y, Chen Y, Lin S, Shu C. Differential autophagic effects of vital dyes in retinal pigment epithelial ARPE-19 and photoreceptor 661W cells. PLoS ONE. 2017;12:e0174736 pubmed publisher
|
Suresh S, Chavalmane A, Dj V, Yarreiphang H, Rai S, Paul A, et al. A novel autophagy modulator 6-Bio ameliorates SNCA/?-synuclein toxicity. Autophagy. 2017;13:1221-1234 pubmed publisher
|
Su X, Liu S, Zhang X, Lam S, Hu X, Zhou Y, et al. Requirement of cytosolic phospholipase A2 gamma in lipid droplet formation. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:692-705 pubmed publisher
|
Ota K, Tong K, Goto K, Tomida S, Komuro A, Wang Z, et al. The H3K27 demethylase, Utx, regulates adipogenesis in a differentiation stage-dependent manner. PLoS ONE. 2017;12:e0173713 pubmed publisher
|
Sechler M, Parrish J, Birks D, Jedlicka P. The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis. Oncogene. 2017;36:4150-4160 pubmed publisher
|
Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, et al. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. 2017;543:568-572 pubmed publisher
|
Coomans de Brachène A, Dif N, de Rocca Serra A, Bonnineau C, Velghe A, Larondelle Y, et al. PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase. FEBS Open Bio. 2017;7:414-423 pubmed publisher
|
Pappas L, Xu X, Abramson D, Jhanwar S. Genomic instability and proliferation/survival pathways in RB1-deficient malignancies. Adv Biol Regul. 2017;64:20-32 pubmed publisher
|
Walters B, Mercaldo V, Gillon C, Yip M, Neve R, BOYCE F, et al. The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation. Neuropsychopharmacology. 2017;42:1502-1510 pubmed publisher
|
Chatterjee S, Huang E, Christie I, Kurland B, Burns T. Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network. Mol Cancer Ther. 2017;16:793-804 pubmed publisher
|
Dahmene M, Bérard M, Oueslati A. Dissecting the Molecular Pathway Involved in PLK2 Kinase-mediated α-Synuclein-selective Autophagic Degradation. J Biol Chem. 2017;292:3919-3928 pubmed publisher
|
Demetriadou A, Morales Sanfrutos J, Nearchou M, Baba O, Kyriacou K, Tate E, et al. Mouse Stbd1 is N-myristoylated and affects ER-mitochondria association and mitochondrial morphology. J Cell Sci. 2017;130:903-915 pubmed publisher
|
Van Hée V, Labar D, Dehon G, Grasso D, Grégoire V, Muccioli G, et al. Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors. Oncotarget. 2017;8:24415-24428 pubmed publisher
|
Kamioka Y, Takakura K, Sumiyama K, Matsuda M. Intravital Förster resonance energy transfer imaging reveals osteopontin-mediated polymorphonuclear leukocyte activation by tumor cell emboli. Cancer Sci. 2017;108:226-235 pubmed publisher
|
Göllner S, Oellerich T, Agrawal Singh S, Schenk T, Klein H, Rohde C, et al. Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat Med. 2017;23:69-78 pubmed publisher
|
Pavel M, Imarisio S, Menzies F, Jimenez Sanchez M, Siddiqi F, Wu X, et al. CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun. 2016;7:13821 pubmed publisher
|
Gokhale A, Hartwig C, Freeman A, Das R, Zlatic S, Vistein R, et al. The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse. J Neurosci. 2016;36:12393-12411 pubmed
|
Faes S, Duval A, Planche A, Uldry E, Santoro T, Pythoud C, et al. Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors. Mol Cancer. 2016;15:78 pubmed
|
Sulaiman A, Sulaiman B, Khouri L, McGarry S, Nessim C, Arnaout A, et al. Both bulk and cancer stem cell subpopulations in triple-negative breast cancer are susceptible to Wnt, HDAC, and ER? coinhibition. FEBS Lett. 2016;590:4606-4616 pubmed publisher
|
Perez Diaz S, García Rodríguez B, Gonzalez Irazabal Y, Valero M, Lagos Lizan J, Arbones Mainar J. Knockdown of PTRF ameliorates adipocyte differentiation and functionality of human mesenchymal stem cells. Am J Physiol Cell Physiol. 2017;312:C83-C91 pubmed publisher
|
Lopez Mosqueda J, Maddi K, Prgomet S, Kalayil S, Marinovic Terzic I, Terzic J, et al. SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks. elife. 2016;5: pubmed publisher
|
Thompson J, Nguyen Q, Singh M, Pavesic M, Nesterenko I, Nelson L, et al. Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma. Oncogene. 2017;36:1080-1089 pubmed publisher
|
Chen W, Xu Y, Zhong J, Wang H, Weng M, Cheng Q, et al. MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway. Oncotarget. 2016;7:78726-78735 pubmed publisher
|
Kawakami H, Huang S, Pal K, Dutta S, Mukhopadhyay D, Sinicrope F. Mutant BRAF Upregulates MCL-1 to Confer Apoptosis Resistance that Is Reversed by MCL-1 Antagonism and Cobimetinib in Colorectal Cancer. Mol Cancer Ther. 2016;15:3015-3027 pubmed
|
Jørgensen S, Coskun M, Homburg K, Pedersen O, Troelsen J. HOXB4 Gene Expression Is Regulated by CDX2 in Intestinal Epithelial Cells. PLoS ONE. 2016;11:e0164555 pubmed publisher
|
Vasconcelos F, Sessa A, Laranjeira C, Raposo A, Teixeira V, Hagey D, et al. MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis. Cell Rep. 2016;17:469-483 pubmed publisher
|
Wang B, McHugh B, Qureshi A, Campopiano D, Clarke D, Fitzgerald J, et al. IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2. J Invest Dermatol. 2017;137:95-105 pubmed publisher
|
Norambuena A, Wallrabe H, McMahon L, Silva A, Swanson E, Khan S, et al. mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease. Alzheimers Dement. 2017;13:152-167 pubmed publisher
|
Hashimoto A, Hashimoto S, Sugino H, Yoshikawa A, Onodera Y, Handa H, et al. ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance. Oncogenesis. 2016;5:e259 pubmed publisher
|
Reid M, Lowman X, Pan M, Tran T, Warmoes M, Ishak Gabra M, et al. IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3. Genes Dev. 2016;30:1837-51 pubmed publisher
|
Li J, Yu H, Xi M, Lu X. Long noncoding RNA C17orf91 is a potential prognostic marker and functions as an oncogene in ovarian cancer. J Ovarian Res. 2016;9:49 pubmed publisher
|
Gusscott S, Jenkins C, Lam S, Giambra V, Pollak M, Weng A. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS ONE. 2016;11:e0161158 pubmed publisher
|
Martin K, Lupey L, Tempera I. Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1. J Virol. 2016;90:8520-30 pubmed publisher
|
Yan J, Fei Y, Han Y, Lu S. Selenoprotein O deficiencies suppress chondrogenic differentiation of ATDC5 cells. Cell Biol Int. 2016;40:1033-40 pubmed publisher
|
Chidley C, Trauger S, Birsoy K, O Shea E. The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine. elife. 2016;5: pubmed publisher
|
Li Q, Qin Y, Wei P, Lian P, Li Y, Xu Y, et al. Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma. Mol Cancer Res. 2016;14:830-40 pubmed publisher
|
Yang J, Shen Z, Jiang X, Yang H, Huang H, Jin L, et al. Agonist-Activated Bombyx Corazonin Receptor Is Internalized via an Arrestin-Dependent and Clathrin-Independent Pathway. Biochemistry. 2016;55:3874-87 pubmed publisher
|
Coskun M, Soendergaard C, Joergensen S, Dahlgaard K, Riis L, Nielsen O, et al. Regulation of Laminin γ2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation. J Cell Biochem. 2017;118:298-307 pubmed publisher
|
Gall B, Schroer A, Gross J, Setola V, Siderovski D. Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model. Genes Immun. 2016;17:321-7 pubmed publisher
|
Cormerais Y, Giuliano S, Lefloch R, Front B, Durivault J, Tambutte E, et al. Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth. Cancer Res. 2016;76:4481-92 pubmed publisher
|
Das F, Dey N, Bera A, Kasinath B, Ghosh Choudhury N, Choudhury G. MicroRNA-214 Reduces Insulin-like Growth Factor-1 (IGF-1) Receptor Expression and Downstream mTORC1 Signaling in Renal Carcinoma Cells. J Biol Chem. 2016;291:14662-76 pubmed publisher
|
Tilston Lünel A, Haley K, Schlecht N, Wang Y, Chatterton A, Moleirinho S, et al. Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells. J Mol Cell Biol. 2016;: pubmed
|
LeNoue Newton M, Wadzinski B, Spiller B. The three Type 2A protein phosphatases, PP2Ac, PP4c and PP6c, are differentially regulated by Alpha4. Biochem Biophys Res Commun. 2016;475:64-9 pubmed publisher
|
Feehan R, Shantz L. Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation. Cell Signal. 2016;28:798-809 pubmed publisher
|
Hashimoto A, Oikawa T, Hashimoto S, Sugino H, Yoshikawa A, Otsuka Y, et al. P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance. J Cell Biol. 2016;213:81-95 pubmed publisher
|
Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
|
Thongon N, Castiglioni I, Zucal C, Latorre E, D Agostino V, Bauer I, et al. The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level. Oncotarget. 2016;7:26551-66 pubmed publisher
|
Takaoka S, Kamioka Y, Takakura K, Baba A, Shime H, Seya T, et al. Live imaging of transforming growth factor-β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acid. Cancer Sci. 2016;107:644-52 pubmed publisher
|
Yalley A, Schill D, Hatta M, Johnson N, Cirillo L. Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes. J Biol Chem. 2016;291:8848-61 pubmed publisher
|
Imakawa K, Dhakal P, Kubota K, Kusama K, Chakraborty D, Karim Rumi M, et al. CITED2 modulation of trophoblast cell differentiation: insights from global transcriptome analysis. Reproduction. 2016;151:509-16 pubmed publisher
|
Wright H, Arulmoli J, Motazedi M, Nelson L, Heinemann F, Flanagan L, et al. CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer. Oncogene. 2016;35:4762-72 pubmed publisher
|
Bado I, Nikolos F, Rajapaksa G, Gustafsson J, Thomas C. ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function. Oncotarget. 2016;7:13599-611 pubmed publisher
|
Prior K, Wittig I, Leisegang M, Groenendyk J, Weissmann N, Michalak M, et al. The Endoplasmic Reticulum Chaperone Calnexin Is a NADPH Oxidase NOX4 Interacting Protein. J Biol Chem. 2016;291:7045-59 pubmed publisher
|
Ji S, Zhang B, Liu J, Qin Y, Liang C, Shi S, et al. ALDOA functions as an oncogene in the highly metastatic pancreatic cancer. Cancer Lett. 2016;374:127-135 pubmed publisher
|
Hashimoto S, Mikami S, Sugino H, Yoshikawa A, Hashimoto A, Onodera Y, et al. Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer. Nat Commun. 2016;7:10656 pubmed publisher
|
Piotrowski Daspit A, Tien J, Nelson C. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integr Biol (Camb). 2016;8:319-31 pubmed publisher
|
Llanos S, GarcÃa Pedrero J, Morgado Palacin L, Rodrigo J, Serrano M. Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers. Nat Commun. 2016;7:10438 pubmed publisher
|
Gall B, Wilson A, Schroer A, Gross J, Stoilov P, Setola V, et al. Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance. Genes Immun. 2016;17:139-47 pubmed publisher
|
He Y, Zeng M, Yang D, Motro B, Núñez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature. 2016;530:354-7 pubmed publisher
|
Jung Y, Nolta J. BMI1 Regulation of Self-Renewal and Multipotency in Human Mesenchymal Stem Cells. Curr Stem Cell Res Ther. 2016;11:131-40 pubmed
|
Hoofd C, Wang X, Lam S, JENKINS C, Wood B, Giambra V, et al. CD44 promotes chemoresistance in T-ALL by increased drug efflux. Exp Hematol. 2016;44:166-71.e17 pubmed publisher
|
Shan Y, Cortopassi G. Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly. Mitochondrion. 2016;26:94-103 pubmed publisher
|
Wu T, Chang S, Li C, Hsu Y, Chen T, Lee W, et al. Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-?B Pathway-Mediated Epithelial-Mesenchymal Transition after Resection. Clin Cancer Res. 2016;22:1800-12 pubmed publisher
|
Foss K, Robeson A, Kornbluth S, Zhang L. Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. Cell Cycle. 2016;15:225-33 pubmed publisher
|
Ruscetti M, Dadashian E, Guo W, Quach B, Mulholland D, Park J, et al. HDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer. Oncogene. 2016;35:3781-95 pubmed publisher
|
Pérez Escuredo J, Dadhich R, Dhup S, Cacace A, Van Hée V, De Saedeleer C, et al. Lactate promotes glutamine uptake and metabolism in oxidative cancer cells. Cell Cycle. 2016;15:72-83 pubmed publisher
|
D Agostino V, Lal P, Mantelli B, Tiedje C, Zucal C, Thongon N, et al. Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function. Sci Rep. 2015;5:16478 pubmed publisher
|
Zucal C, D Agostino V, Casini A, Mantelli B, Thongon N, Soncini D, et al. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. BMC Cancer. 2015;15:855 pubmed publisher
|
Birket M, Ribeiro M, Kosmidis G, Ward D, Leitoguinho A, van de Pol V, et al. Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function. Cell Rep. 2015;13:733-745 pubmed publisher
|
Duan L, Perez R, Davaadelger B, Dedkova E, Blatter L, Maki C. p53-regulated autophagy is controlled by glycolysis and determines cell fate. Oncotarget. 2015;6:23135-56 pubmed
|
Lee D, Forscher C, Di Vizio D, Koeffler H. Induction of p53-independent apoptosis by ectopic expression of HOXA5 in human liposarcomas. Sci Rep. 2015;5:12580 pubmed publisher
|
Kruse C, Kurz A, Pálfi K, Humbert P, Sperandio M, Brandes R, et al. Polarity Protein Scrib Facilitates Endothelial Inflammatory Signaling. Arterioscler Thromb Vasc Biol. 2015;35:1954-62 pubmed publisher
|
Hui K, Cheung A, Choi C, Yeung P, Middeldorp J, Lung M, et al. Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. Int J Cancer. 2016;138:125-36 pubmed publisher
|
Taylor I, Hütt Cabezas M, Brandt W, Kambhampati M, Nazarian J, Chang H, et al. Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition. J Neuropathol Exp Neurol. 2015;74:778-90 pubmed publisher
|
Hayashi M, Cesare A, Rivera T, Karlseder J. Cell death during crisis is mediated by mitotic telomere deprotection. Nature. 2015;522:492-6 pubmed publisher
|
Wang Y, Yang C, Gu Q, Sims M, Gu W, Pfeffer L, et al. KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells. PLoS ONE. 2015;10:e0130341 pubmed publisher
|
Witwicka H, Jia H, Kutikov A, Reyes Gutiérrez P, Li X, Odgren P. TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption. PLoS ONE. 2015;10:e0127537 pubmed publisher
|
Kan R, Shuen W, Lung H, Cheung A, Dai W, Kwong D, et al. NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells. PLoS ONE. 2015;10:e0127239 pubmed publisher
|
Paran C, Verkerke A, Heden T, Park S, Zou K, Lawson H, et al. Reduced efficiency of sarcolipin-dependent respiration in myocytes from humans with severe obesity. Obesity (Silver Spring). 2015;23:1440-9 pubmed publisher
|
Cheung A, Ip J, Chu A, Cheng Y, Leong M, Ko J, et al. PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma. Oncotarget. 2015;6:13434-47 pubmed
|
Sengupta D, Kannan A, Kern M, Moreno M, Vural E, Stack B, et al. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma. Epigenetics. 2015;10:460-6 pubmed publisher
|
Mishra D, Chaudhary S, Krishna B, Mishra S. Identification of Critical Elements for Regulation of Inorganic Pyrophosphatase (PPA1) in MCF7 Breast Cancer Cells. PLoS ONE. 2015;10:e0124864 pubmed publisher
|
Carvalho S, Lindzen M, Lauriola M, Shirazi N, Sinha S, Abdul Hai A, et al. An antibody to amphiregulin, an abundant growth factor in patients' fluids, inhibits ovarian tumors. Oncogene. 2016;35:438-47 pubmed publisher
|
Jimenez Sanchez M, Lam W, Hannus M, Sönnichsen B, Imarisio S, Fleming A, et al. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Nat Chem Biol. 2015;11:347-354 pubmed publisher
|
Ip J, Ko J, Yu V, Chan K, Lam A, Law S, et al. A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma. Biomed Res Int. 2015;2015:910715 pubmed publisher
|
Sample V, Ramamurthy S, Gorshkov K, Ronnett G, Zhang J. Polarized activities of AMPK and BRSK in primary hippocampal neurons. Mol Biol Cell. 2015;26:1935-46 pubmed publisher
|
Papp S, Huber A, Jordan S, Kriebs A, Nguyen M, Moresco J, et al. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. elife. 2015;4: pubmed publisher
|
Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, et al. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer. Cell Res. 2015;25:561-73 pubmed publisher
|
Bruserud Ã, Reikvam H, Fredly H, Skavland J, Hagen K, van Hoang T, et al. Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation. Oncotarget. 2015;6:2794-811 pubmed
|
Niemeyer B, Parrish J, Spoelstra N, Joyal T, Richer J, Jedlicka P. Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. PLoS ONE. 2015;10:e0116895 pubmed publisher
|
Karakashev S, Reginato M. Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2. Oncotarget. 2015;6:1967-80 pubmed
|
Tomida J, Takata K, Lange S, Schibler A, Yousefzadeh M, Bhetawal S, et al. REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ?. Nucleic Acids Res. 2015;43:1000-11 pubmed publisher
|
Vijayakumar V, Monypenny J, Chen X, Machesky L, Lilla S, Thrasher A, et al. Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages. J Cell Sci. 2015;128:251-65 pubmed publisher
|
Tan Y, Kim M, Kingsbury T, Civin C, Cheng W. Regulation of RAB5C is important for the growth inhibitory effects of MiR-509 in human precursor-B acute lymphoblastic leukemia. PLoS ONE. 2014;9:e111777 pubmed publisher
|
Geiger T, Ha N, Faraji F, Michael H, Rodriguez L, Walker R, et al. Functional analysis of prognostic gene expression network genes in metastatic breast cancer models. PLoS ONE. 2014;9:e111813 pubmed publisher
|
Charni Chaabane S, Coomans de Brachène A, Essaghir A, Velghe A, Lo Re S, Stockis J, et al. PDGF-D expression is down-regulated by TGFβ in fibroblasts. PLoS ONE. 2014;9:e108656 pubmed publisher
|
Xu X, Singh H, Wang L, Qi D, Poulos B, Abramson D, et al. Rb suppresses human cone-precursor-derived retinoblastoma tumours. Nature. 2014;514:385-8 pubmed publisher
|
Tripathi R, Ash D, Shaha C. Beclin-1-p53 interaction is crucial for cell fate determination in embryonal carcinoma cells. J Cell Mol Med. 2014;18:2275-86 pubmed publisher
|
Bailey S, Zhou B, Damrauer J, Krishnan B, Wilson H, Smith A, et al. mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma. PLoS ONE. 2014;9:e104413 pubmed publisher
|
Baskin R, Park S, Keserű G, Bisht K, Wamsley H, Sayeski P. The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo. PLoS ONE. 2014;9:e105568 pubmed publisher
|
Yang C, Matsuura K, Huang N, Robeson A, Huang B, Zhang L, et al. Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death. Oncogene. 2015;34:3264-72 pubmed publisher
|
Ye J, Kim N, Lee K, Nam Y, Lee U, Joo C. Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein. J Virol. 2014;88:12765-76 pubmed publisher
|
Ruas M, Chuang K, Davis L, Al Douri A, Tynan P, Tunn R, et al. TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2. Mol Cell Biol. 2014;34:3981-92 pubmed publisher
|
Yao W, Ji S, Qin Y, Yang J, Xu J, Zhang B, et al. Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1? axis. Mol Cancer. 2014;13:187 pubmed publisher
|
Gagliardi P, di Blasio L, Puliafito A, Seano G, Sessa R, Chianale F, et al. PDK1-mediated activation of MRCK? regulates directional cell migration and lamellipodia retraction. J Cell Biol. 2014;206:415-34 pubmed publisher
|
Bieler J, Cannavò R, Gustafson K, Gobet C, Gatfield D, Naef F. Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells. Mol Syst Biol. 2014;10:739 pubmed publisher
|
Khosravi R, Sodek K, Xu W, Bais M, Saxena D, Faibish M, et al. A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia. PLoS ONE. 2014;9:e100669 pubmed publisher
|
de Renty C, DePamphilis M, Ullah Z. Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis. PLoS ONE. 2014;9:e97434 pubmed publisher
|
Alcaraz L, Exposito J, Chuvin N, Pommier R, Cluzel C, Martel S, et al. Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-?. J Cell Biol. 2014;205:409-28 pubmed publisher
|
Fischer S, Ronellenfitsch M, Thiepold A, Harter P, Reichert S, Kogel D, et al. Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid. PLoS ONE. 2014;9:e94921 pubmed publisher
|
Diaz J, Mendoza P, Ortiz R, Diaz N, Leyton L, Stupack D, et al. Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion. J Cell Sci. 2014;127:2401-6 pubmed publisher
|
Muller K, Zurbriggen M, Weber W. Control of gene expression using a red- and far-red light-responsive bi-stable toggle switch. Nat Protoc. 2014;9:622-32 pubmed publisher
|
Zhang X, Liu Q, Luo C, Deng Y, Cui K, Shi D. Identification and characterization of buffalo 7SK and U6 pol III promoters and application for expression of short hairpin RNAs. Int J Mol Sci. 2014;15:2596-607 pubmed publisher
|
O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher
|
Birket M, Casini S, Kosmidis G, Elliott D, Gerencser A, Baartscheer A, et al. PGC-1? and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function. Stem Cell Reports. 2013;1:560-74 pubmed publisher
|
Munkley J, Rajan P, Lafferty N, Dalgliesh C, Jackson R, Robson C, et al. A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation. Oncotarget. 2014;5:131-9 pubmed
|
Li Z, Dong L, Dean E, Yang L. Acidosis decreases c-Myc oncogene expression in human lymphoma cells: a role for the proton-sensing G protein-coupled receptor TDAG8. Int J Mol Sci. 2013;14:20236-55 pubmed publisher
|
Cheng Y, Cheung A, Ko J, Phoon Y, Chiu P, Lo P, et al. Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma. BMC Cell Biol. 2013;14:44 pubmed publisher
|
Gow C, Guo C, Wang D, Hu Q, Zhang J. Differential involvement of E2A-corepressor interactions in distinct leukemogenic pathways. Nucleic Acids Res. 2014;42:137-52 pubmed publisher
|
Jiang H, Lu X, Shimada M, Dou Y, Tang Z, Roeder R. Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95. Nat Struct Mol Biol. 2013;20:1156-63 pubmed publisher
|
Salloum S, Wang H, Ferguson C, Parton R, Tai A. Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets. PLoS Pathog. 2013;9:e1003513 pubmed publisher
|
Mao X, Hütt Cabezas M, Orr B, Weingart M, Taylor I, Rajan A, et al. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 2013;4:1050-64 pubmed
|
Ge Y, Waldemer R, Nalluri R, Nuzzi P, Chen J. RNAi screen reveals potentially novel roles of cytokines in myoblast differentiation. PLoS ONE. 2013;8:e68068 pubmed publisher
|
Baird B, Schliekelman M, Ahn Y, Chen Y, Roybal J, Gill B, et al. Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. PLoS ONE. 2013;8:e67054 pubmed publisher
|
Zenzmaier C, Sampson N, Plas E, Berger P. Dickkopf-related protein 3 promotes pathogenic stromal remodeling in benign prostatic hyperplasia and prostate cancer. Prostate. 2013;73:1441-52 pubmed publisher
|
Lee D, Amanat S, Goff C, Weiss L, Said J, Doan N, et al. Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival. Oncogenesis. 2013;2:e47 pubmed publisher
|
Ryder P, Vistein R, Gokhale A, Seaman M, Puthenveedu M, Faundez V. The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα. Mol Biol Cell. 2013;24:2269-84 pubmed publisher
|
Rybak A, Ingram A, Tang D. Propagation of human prostate cancer stem-like cells occurs through EGFR-mediated ERK activation. PLoS ONE. 2013;8:e61716 pubmed publisher
|
Kuroda K, Kuang S, Taketo M, Rudnicki M. Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts. Skelet Muscle. 2013;3:5 pubmed publisher
|
Feldman D, Chen C, Punj V, Machida K. The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. PLoS ONE. 2013;8:e57312 pubmed publisher
|
Zinn R, Gardner E, Dobromilskaya I, Murphy S, Marchionni L, Hann C, et al. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol Cancer. 2013;12:16 pubmed publisher
|
Burns T, Dobromilskaya I, Murphy S, Gajula R, Thiyagarajan S, Chatley S, et al. Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer. Mol Cancer Res. 2013;11:329-38 pubmed publisher
|
Giambra V, Jenkins C, Wang H, Lam S, Shevchuk O, Nemirovsky O, et al. NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-? and reactive oxygen species. Nat Med. 2012;18:1693-8 pubmed publisher
|
Durán R, MacKenzie E, Boulahbel H, Frezza C, Heiserich L, Tardito S, et al. HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Oncogene. 2013;32:4549-56 pubmed publisher
|
De Saedeleer C, Copetti T, Porporato P, Verrax J, Feron O, Sonveaux P. Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells. PLoS ONE. 2012;7:e46571 pubmed publisher
|
Moleirinho S, Chang N, Sims A, Tilston Lünel A, Angus L, Steele A, et al. KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals. Oncogene. 2013;32:1821-30 pubmed publisher
|
Malek M, Guillaumot P, Huber A, Lebeau J, Petrilli V, Kfoury A, et al. LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation. Cell Death Dis. 2012;3:e300 pubmed publisher
|
Diez H, Garrido J, Wandosell F. Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons. PLoS ONE. 2012;7:e32715 pubmed publisher
|
Sonveaux P, Copetti T, De Saedeleer C, Vegran F, Verrax J, Kennedy K, et al. Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. PLoS ONE. 2012;7:e33418 pubmed publisher
|
Stafa K, Trancikova A, Webber P, Glauser L, West A, Moore D. GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1. PLoS Genet. 2012;8:e1002526 pubmed publisher
|
Xing L, Yao X, Williams K, Bassell G. Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis. Mol Biol Cell. 2012;23:1500-9 pubmed publisher
|
Woods M, Kelly J, Hattlmann C, Tong J, Xu L, Coleman M, et al. Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. Retrovirology. 2011;8:95 pubmed publisher
|
Crosnier C, Bustamante L, Bartholdson S, Bei A, Theron M, Uchikawa M, et al. Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum. Nature. 2011;480:534-7 pubmed publisher
|
Uygur B, Wu W. SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis. Mol Cancer. 2011;10:139 pubmed publisher
|
Waldron T, De Dominici M, Soliera A, Audia A, Iacobucci I, Lonetti A, et al. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells. Leukemia. 2012;26:644-53 pubmed publisher
|
Potts R, Zhang P, Wurster A, Precht P, Mughal M, Wood W, et al. CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. PLoS ONE. 2011;6:e24515 pubmed publisher
|
Fink L, Roell M, Caiazza E, Lerner C, STAMATO T, Hrelia S, et al. 53BP1 contributes to a robust genomic stability in human fibroblasts. Aging (Albany NY). 2011;3:836-45 pubmed
|
Kazi A, Hong Brown L, Lang S, Lang C. Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy. Mol Med. 2011;17:925-36 pubmed publisher
|
Alekseev O, Richardson R, TSURUTA J, O Rand M. Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells. Reprod Biol Endocrinol. 2011;9:50 pubmed publisher
|
Kawazu M, Saso K, Tong K, McQuire T, Goto K, Son D, et al. Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development. PLoS ONE. 2011;6:e17830 pubmed publisher
|
Zlatic S, Tornieri K, L hernault S, Faundez V. Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells. Mol Biol Cell. 2011;22:1699-715 pubmed publisher
|
Bell E, Emerling B, Ricoult S, Guarente L. SirT3 suppresses hypoxia inducible factor 1? and tumor growth by inhibiting mitochondrial ROS production. Oncogene. 2011;30:2986-96 pubmed publisher
|
Nowak U, Matthews A, Zheng S, Chaudhuri J. The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA. Nat Immunol. 2011;12:160-6 pubmed publisher
|
Martín Villar E, Fernández Muñoz B, Parsons M, Yurrita M, Megias D, Perez Gomez E, et al. Podoplanin associates with CD44 to promote directional cell migration. Mol Biol Cell. 2010;21:4387-99 pubmed publisher
|
Lin F, Chang C, Cheong M, Chen H, Lee D, Chang G, et al. Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation. Nucleic Acids Res. 2011;39:848-61 pubmed publisher
|
Bitto A, Lerner C, Torres C, Roell M, Malaguti M, Perez V, et al. Long-term IGF-I exposure decreases autophagy and cell viability. PLoS ONE. 2010;5:e12592 pubmed publisher
|
Patel S, Simon M. Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. J Biol Chem. 2010;285:15587-98 pubmed publisher
|
Torres V, Mielgo A, Barbero S, Hsiao R, Wilkins J, Stupack D. Rab5 mediates caspase-8-promoted cell motility and metastasis. Mol Biol Cell. 2010;21:369-76 pubmed publisher
|
Smith K, Fu M, Brown E. Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis. J Cell Biol. 2009;187:15-23 pubmed publisher
|
Chen M, Philipp M, Wang J, Premont R, Garrison T, Caron M, et al. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. J Biol Chem. 2009;284:35040-8 pubmed publisher
|
Copp J, Manning G, Hunter T. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Res. 2009;69:1821-7 pubmed publisher
|
Kulkarni A, McNeill D, Gleichmann M, Mattson M, Wilson D. XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells. Nucleic Acids Res. 2008;36:5111-21 pubmed publisher
|
Barr S, Smiley J, Bushman F. The interferon response inhibits HIV particle production by induction of TRIM22. PLoS Pathog. 2008;4:e1000007 pubmed publisher
|
Sarbassov D, Guertin D, Ali S, Sabatini D. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science. 2005;307:1098-101 pubmed
|