This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
myc-Raptor
catalog :
1859
citations: 9
Reference
Ganner A, Gehrke C, Klein M, Thegtmeier L, Matulenski T, Wingendorf L, et al. VHL suppresses RAPTOR and inhibits mTORC1 signaling in clear cell renal cell carcinoma. Sci Rep. 2021;11:14827 pubmed publisher
Chawsheen M, Dash P. mTOR modulates resistance to gemcitabine in lung cancer in an MTORC2 dependent mechanism. Cell Signal. 2021;81:109934 pubmed publisher
Seo S, Woo S, Lee H, Kim S, Min K, Kwon T. mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy. Oncogene. 2018;37:5205-5220 pubmed publisher
Liu D, Ceddia R, Collins S. Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1. Mol Metab. 2018;9:192-198 pubmed publisher
Manifava M, Smith M, Rotondo S, Walker S, Niewczas I, Zoncu R, et al. Dynamics of mTORC1 activation in response to amino acids. elife. 2016;5: pubmed publisher
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
Hao F, Itoh T, Morita E, Shirahama Noda K, Yoshimori T, Noda T. The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity. FEBS Lett. 2016;590:161-73 pubmed publisher
Robles Molina E, Dionisio Vicuña M, Guzmán Hernández M, Reyes Cruz G, Vazquez Prado J. G?? interacts with mTOR and promotes its activation. Biochem Biophys Res Commun. 2014;444:218-23 pubmed publisher
Sarbassov D, Ali S, Kim D, Guertin D, Latek R, Erdjument Bromage H, et al. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol. 2004;14:1296-302 pubmed
product information
Catalog Number :
1859
Product Name :
myc-Raptor
article :
doi10.1016/j.cub.2004.06.054
id129
pubmed_id15268862
bacterial resistance :
Ampicillin
cloning :
backbonepRK-5
backbone_mutation
backbone_originBD Pharmingen
backbone_size4754
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5SalI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesKOG1, Mip1
geneRPTOR
id57521
genbank_ids
mutation
nameRaptor
shRNA_sequence
size6000
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
resistance markers :
432
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA