This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pAAV-hSyn-GFP-IRES-hSNCA (A11P/V70P)
catalog :
185717
citations: 1
Reference
Albarran E, Sun Y, Liu Y, Raju K, Dong A, Li Y, et al. Postsynaptic synucleins mediate endocannabinoid signaling. Nat Neurosci. 2023;26:997-1007 pubmed publisher
product information
Catalog Number :
185717
Product Name :
pAAV-hSyn-GFP-IRES-hSNCA (A11P/V70P)
article :
doi10.1038/s41593-023-01345-0
id28225278
pubmed_id37248337
bacterial resistance :
Ampicillin
cloning :
backbonepAAV-hSyn-EGFP
backbone_mutation
backbone_origin
backbone_size4874
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
AAV
growth notes :
Please visit https://www.biorxiv.org/content/10.1101/2021.10.04.462870v1 for bioRxiv preprint.
growth strain :
AAV expression of GFP and human -Synuclein with A11P and V70P mutations from hSyn promoter
origin :
30
pi :
alt_names
SNCA
cloning
clone_methodRestriction Enzyme
cloning_site_3NheI
cloning_site_5SalI
promoterhSyn
sequencing_primer_3WPRE-R
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesNACP, PARK1, PARK4, PD1
geneSNCA
id6622
genbank_ids
NM_000345
mutationChanged Ala 11 to Pro, Val 70 to Pro
namesynuclein, alpha
shRNA_sequence
size423
species
9606
Homo sapiens
tags
plasmid copy :
Thomas C. S dhof, Stanford
resistance markers :
5999
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA