This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
GFP-Bcl2
catalog :
17999
citations: 10
Reference
Lalier L, Mignard V, Joalland M, Lanoë D, Cartron P, Manon S, et al. TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis. Cell Death Dis. 2021;12:182 pubmed publisher
Castro Gonzalez S, Shi Y, Colomer Lluch M, Song Y, Mowery K, Almodovar S, et al. HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner. Autophagy. 2020;:1-25 pubmed publisher
Lunova M, Smolková B, Uzhytchak M, Janoušková K, Jirsa M, Egorova D, et al. Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations. Cell Mol Life Sci. 2020;77:2815-2838 pubmed publisher
Sun X, Angelastro J, Merino D, Zhou Q, Siegelin M, Greene L. Dominant-negative ATF5 rapidly depletes survivin in tumor cells. Cell Death Dis. 2019;10:709 pubmed publisher
Wu L, Xie J, Li T, Mai Z, Wang L, Wang X, et al. Gene delivery ability of polyethylenimine and polyethylene glycol dual-functionalized nanographene oxide in 11 different cell lines. R Soc Open Sci. 2017;4:170822 pubmed publisher
Su Y, Guo X, Qi X. Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy. Biochim Biophys Acta. 2015;1852:12-21 pubmed publisher
Sarkar S, Azab B, Quinn B, Shen X, Dent P, Klibanov A, et al. Chemoprevention gene therapy (CGT) of pancreatic cancer using perillyl alcohol and a novel chimeric serotype cancer terminator virus. Curr Mol Med. 2014;14:125-40 pubmed
Ferdek P, Gerasimenko J, Peng S, Tepikin A, Petersen O, Gerasimenko O. A novel role for Bcl-2 in regulation of cellular calcium extrusion. Curr Biol. 2012;22:1241-6 pubmed publisher
Gerasimenko J, Ferdek P, Fischer L, Gukovskaya A, Pandol S. Inhibitors of Bcl-2 protein family deplete ER Ca2+ stores in pancreatic acinar cells. Pflugers Arch. 2010;460:891-900 pubmed publisher
Wang N, Unkila M, Reineks E, Distelhorst C. Transient expression of wild-type or mitochondrially targeted Bcl-2 induces apoptosis, whereas transient expression of endoplasmic reticulum-targeted Bcl-2 is protective against Bax-induced cell death. J Biol Chem. 2001;276:44117-28 pubmed
product information
Catalog Number :
17999
Product Name :
GFP-Bcl2
article :
doi10.1074/jbc.M101958200
id2100
pubmed_id11546793
bacterial resistance :
Kanamycin
cloning :
backbonepEMD-C1
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Bcl2
cloning
clone_methodRestriction Enzyme
cloning_site_3Eco RI
cloning_site_5Bgl II
promoterCMV
sequencing_primer_3
sequencing_primer_5CATGGTCCTGCTGGAGTTCGT
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBcl-2, PPP1R50
geneBCL2
id596
genbank_ids
mutation
nameBcl-2
shRNA_sequence
size720
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
plasmid copy :
human Bcl-2 was PCR amplified from pB4 plasmid purchased from ATCC
resistance markers :
117
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA