This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFP-NR2B
catalog :
17925
citations: 10
Reference
Li A, Li W, Ali T, Yang C, Liu Z, Gao R, et al. A novel dopamine D2 receptor-NR2B protein complex might contribute to morphine use disorders. Eur J Pharmacol. 2023;961:176174 pubmed publisher
Parnell E, Voorn R, Martín de Saavedra M, Loizzo D, Dos Santos M, Penzes P. A developmental delay linked missense mutation in Kalirin-7 disrupts protein function and neuronal morphology. Front Mol Neurosci. 2022;15:994513 pubmed publisher
Lee G, Zhang J, Wu Y, Zhou Y. 14-3-3 proteins promote synaptic localization of N-methyl d-aspartate receptors (NMDARs) in mouse hippocampal and cortical neurons. PLoS ONE. 2021;16:e0261791 pubmed publisher
G xf3 mez R, Maglio L, Gonzalez Hernandez A, Rivero P xe9 rez B, Bartolom xe9 Mart xed n D, Giraldez T. NMDA receptor-BK channel coupling regulates synaptic plasticity in the barrel cortex. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Mehta N, Maddineni S, Kelly R, Lee R, Hunter S, Silberstein J, et al. An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA. Sci Rep. 2020;10:15171 pubmed publisher
Sceniak M, Fedder K, Wang Q, Droubi S, Babcock K, Patwardhan S, et al. An autism-associated mutation in GluN2B prevents NMDA receptor trafficking and interferes with dendrite growth. J Cell Sci. 2019;132: pubmed publisher
Reyes Guzman E, Vega Castro N, Reyes Montaño E, Recio Pinto E. Antagonistic action on NMDA/GluN2B mediated currents of two peptides that were conantokin-G structure-based designed. BMC Neurosci. 2017;18:44 pubmed publisher
Chakraborty M, Chen L, Fridel E, Klein M, Senft R, Sarkar A, et al. Overexpression of human NR2B receptor subunit in LMAN causes stuttering and song sequence changes in adult zebra finches. Sci Rep. 2017;7:942 pubmed publisher
Bagasrawala I, Memi F, V Radonjić N, Zecevic N. N-Methyl d-Aspartate Receptor Expression Patterns in the Human Fetal Cerebral Cortex. Cereb Cortex. 2017;27:5041-5053 pubmed publisher
Luo J, Fu Z, Losi G, Kim B, Prybylowski K, Vissel B, et al. Functional expression of distinct NMDA channel subunits tagged with green fluorescent protein in hippocampal neurons in culture. Neuropharmacology. 2002;42:306-18 pubmed
product information
Catalog Number :
17925
Product Name :
pEGFP-NR2B
article :
doi10.1016/S0028-3908(01)00188-5
id2085
pubmed_id11897109
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4716
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Addgene NGS identified a few sequence discrepancies relative to Genbank ID: M91562, but the plasmid is expected to function as described in the associated publication.
origin :
37
pi :
alt_names
NR2B
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoR1
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGluN2B
geneGrin2b
id24410
genbank_ids
mutation
nameN-methyl D-aspartate receptor 2B
shRNA_sequence
size5291
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tageGFP
resistance markers :
551
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA