This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBabe-c-myc-zeo
catalog :
17758
citations: 9
Reference
Huo Q, Li K, Sun X, Zhuang A, Minami K, Tamari K, et al. The inhibition of pancreatic cancer progression by K-Ras-overexpressing mesenchymal stem cell-derived secretomes. Sci Rep. 2023;13:15036 pubmed publisher
Li K, Sun X, Minami K, Tamari K, Ogawa K, Li H, et al. Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis. Theranostics. 2023;13:1247-1263 pubmed publisher
Li K, Sun X, Zha R, Liu S, Feng Y, Sano T, et al. Counterintuitive production of tumor-suppressive secretomes from Oct4- and c-Myc-overexpressing tumor cells and MSCs. Theranostics. 2022;12:3084-3103 pubmed publisher
Zhan H, Bhattacharya S, Cai H, Iglesias P, Huang C, Devreotes P. An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells. Dev Cell. 2020;54:608-623.e5 pubmed publisher
Wang M, LAW M, Davis B, Yaaghubi E, Ghilardi A, Ferreira R, et al. Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway. Cell Death Discov. 2019;5:153 pubmed publisher
Hanaford A, Alt J, Rais R, Wang S, Kaur H, Thorek D, et al. Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma. Transl Oncol. 2019;12:1314-1322 pubmed publisher
Wang S, Poore B, Alt J, Price A, Allen S, Hanaford A, et al. Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine. Clin Cancer Res. 2019;25:5925-5936 pubmed publisher
Hanaford A, Archer T, Price A, Kahlert U, Maciaczyk J, Nikkhah G, et al. DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. Clin Cancer Res. 2016;22:3903-14 pubmed publisher
Dai C, Whitesell L, Rogers A, Lindquist S. Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell. 2007;130:1005-18 pubmed
product information
Catalog Number :
17758
Product Name :
pBabe-c-myc-zeo
article :
doi10.1016/j.cell.2007.07.020
id1356
pubmed_id17889646
bacterial resistance :
Ampicillin
cloning :
backbonepBABE-zeo
backbone_mutation
backbone_origin
backbone_size4800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
This is the p64 transcript variant of c-myc
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3pBABE3'
sequencing_primer_5pBABE5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
mutation
namec-myc
shRNA_sequence
size1400
species
9606
Homo sapiens
tags
plasmid copy :
Dr. Weinberg, Whitehead Institute
resistance markers :
293
tags :
High Copy
terms :
Zeocin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA