This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcSrc527
catalog :
17675
citations: 4
Reference
Jeong J, Park H, Chi G, Choi Y, Park S. An Ethanol Extract of Perilla frutescens Leaves Suppresses Adrenergic Agonist-Induced Metastatic Ability of Cancer Cells by Inhibiting Src-Mediated EMT. Molecules. 2023;28: pubmed publisher
Park H, Chi G, Choi Y, Park S. The root bark of Morus alba L. regulates tumor-associated macrophages by blocking recruitment and M2 polarization of macrophages. Phytother Res. 2020;34:3333-3344 pubmed publisher
Bazzani L, Donnini S, Finetti F, Christofori G, Ziche M. PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells. Oncotarget. 2017;8:31270-31287 pubmed publisher
Kmiecik T, Shalloway D. Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation. Cell. 1987;49:65-73 pubmed
product information
Catalog Number :
17675
Product Name :
pcSrc527
article :
doi10.1016/0092-8674(87)90756-2
id2016
pubmed_id3103925
bacterial resistance :
Ampicillin
cloning :
backbonepEVX
backbone_mutation
backbone_origin
backbone_size6400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Based on plasmid pM5HHB5.
origin :
37
pi :
alt_names
c-Src
src
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPP60C-SCR, SDR, c-src
geneSRC
id396442
genbank_ids
mutationTyr 527 changed to Phe . Activates transforming and kinase activities.
namec-src Y527F
shRNA_sequence
size
species
9031
Gallus gallus
tags
resistance markers :
460
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA