This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Flag-hCRM1
catalog :
17647
citations: 11
Reference
Han T, Jiang S, Zheng H, Yin Q, Xie M, Little M, et al. Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nat Commun. 2019;10:3716 pubmed publisher
Kung J, Jura N. The pseudokinase TRIB1 toggles an intramolecular switch to regulate COP1 nuclear export. EMBO J. 2019;38: pubmed publisher
Cruz Ramos E, Sandoval Hernández A, Tecalco Cruz A. Differential expression and molecular interactions of chromosome region maintenance 1 and calreticulin exportins in breast cancer cells. J Steroid Biochem Mol Biol. 2019;185:7-16 pubmed publisher
Archbold H, Jackson K, Arora A, Weskamp K, Tank E, Li X, et al. TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia. Sci Rep. 2018;8:4606 pubmed publisher
Knittle A, Helkkula M, Johnson M, Sundvall M, Elenius K. SUMOylation regulates nuclear accumulation and signaling activity of the soluble intracellular domain of the ErbB4 receptor tyrosine kinase. J Biol Chem. 2017;292:19890-19904 pubmed publisher
Pentecost M, Vashisht A, Lester T, Voros T, Beaty S, Park A, et al. Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS Pathog. 2015;11:e1004739 pubmed publisher
Dave S, Nanduri R, Dkhar H, Bhagyaraj E, Rao A, Gupta P. Nuclear MEK1 sequesters PPAR? and bisects MEK1/ERK signaling: a non-canonical pathway of retinoic acid inhibition of adipocyte differentiation. PLoS ONE. 2014;9:e100862 pubmed publisher
Beckham T, Cheng J, Lu P, Marrison S, Norris J, Liu X. Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. PLoS ONE. 2013;8:e76593 pubmed publisher
Corum D, Tsichlis P, Muise Helmericks R. AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1. FASEB J. 2014;28:395-407 pubmed publisher
Maiuri T, Woloshansky T, Xia J, Truant R. The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal. Hum Mol Genet. 2013;22:1383-94 pubmed publisher
Wang W, Budhu A, Forgues M, Wang X. Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication. Nat Cell Biol. 2005;7:823-30 pubmed
product information
Catalog Number :
17647
Product Name :
Flag-hCRM1
article :
doi10.1038/ncb1282
id1014
pubmed_id16041368
bacterial resistance :
Ampicillin
cloning :
backbonep3xFLAG CMV-10
backbone_mutation
backbone_originSigma
backbone_size6400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCRM-1, CRM1, emb, exp1
geneXPO1
id7514
genbank_ids
mutation
nameCRM1
shRNA_sequence
size3300
species
9606
Homo sapiens
tags
locationN terminal on insert
tag3x Flag
resistance markers :
562
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA