This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
GFP-NPM WT
catalog :
17578
citations: 25
Reference
Pham A, Mani M, Wang X, Vafabakhsh R. The Physical Biology of Nucleolus Disassembly. bioRxiv. 2023;: pubmed publisher
Sheu Gruttadauria J, Yan X, Stuurman N, Floor S, Vale R. Nucleolar dynamics are determined by the ordered assembly of the ribosome. bioRxiv. 2023;: pubmed publisher
Torrino S, Oldham W, Tejedor A, Burgos I, Rachedi N, Fraissard K, et al. Mechano-dependent sorbitol accumulation supports biomolecular condensate. bioRxiv. 2023;: pubmed publisher
Klump B, Perez G, Patrick E, Adams Boone K, Cohen S, Han L, et al. TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly. Cell Rep. 2023;42:112577 pubmed publisher
Cicardi M, Hallgren J, Mawrie D, Krishnamurthy K, Markandaiah S, Nelson A, et al. C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress. bioRxiv. 2023;: pubmed publisher
Tan P, Hong T, Cai X, Li W, Huang Y, He L, et al. Optical control of protein delivery and partitioning in the nucleolus. Nucleic Acids Res. 2022;: pubmed publisher
Chen C, Yamanaka Y, Ueda K, Li P, Miyagi T, Harada Y, et al. Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine. J Cell Biol. 2021;220: pubmed publisher
Freibaum B, Messing J, Yang P, Kim H, Taylor J. High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate. J Cell Biol. 2021;220: pubmed publisher
Sorokin D, Arifulin E, Vassetzky Y, Sheval E. Live-Cell Imaging and Analysis of Nuclear Body Mobility. Methods Mol Biol. 2020;2175:1-9 pubmed publisher
Shubina M, Arifulin E, Sorokin D, Sosina M, Tikhomirova M, Serebryakova M, et al. The GAR domain integrates functions that are necessary for the proper localization of fibrillarin (FBL) inside eukaryotic cells. Peerj. 2020;8:e9029 pubmed publisher
Hiregange D, Naick H, Rao B. ATR signalling mediates the prosurvival function of phospho-NPM against PIDDosome mediated cell death. Cell Signal. 2020;71:109602 pubmed publisher
Andrade N, Ramic M, Esanov R, Liu W, Rybin M, Gaidosh G, et al. Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD. Mol Neurodegener. 2020;15:13 pubmed publisher
Arifulin E, Sorokin D, Tvorogova A, Kurnaeva M, Musinova Y, Zhironkina O, et al. Heterochromatin restricts the mobility of nuclear bodies. Chromosoma. 2018;127:529-537 pubmed publisher
Glushonkov O, Real E, Boutant E, Mely Y, Didier P. Optimized protocol for combined PALM-dSTORM imaging. Sci Rep. 2018;8:8749 pubmed publisher
Zajac M, Dolnik A, Stasiak G, Zaleska J, Kielbus M, Czapinski J, et al. Analysis of NPM1 splice variants reveals differential expression patterns of prognostic value in acute myeloid leukemia. Oncotarget. 2017;8:95163-95175 pubmed publisher
Wu L, Xie J, Li T, Mai Z, Wang L, Wang X, et al. Gene delivery ability of polyethylenimine and polyethylene glycol dual-functionalized nanographene oxide in 11 different cell lines. R Soc Open Sci. 2017;4:170822 pubmed publisher
Wang T, Liu M, Zheng S, Bian D, Zhang J, Yao J, et al. Tumor-associated autoantibodies are useful biomarkers in immunodiagnosis of ?-fetoprotein-negative hepatocellular carcinoma. World J Gastroenterol. 2017;23:3496-3504 pubmed publisher
Farg M, Konopka A, Soo K, Ito D, Atkin J. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis. Hum Mol Genet. 2017;26:2882-2896 pubmed publisher
Lee K, Zhang P, Kim H, Mitrea D, Sarkar M, Freibaum B, et al. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell. 2016;167:774-788.e17 pubmed publisher
Pfister J, D Mello S. Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status. J Biol Chem. 2016;291:20787-97 pubmed publisher
Dai L, Li J, Xing M, Sanchez T, Casiano C, Zhang J. Using Serological Proteome Analysis to Identify Serum Anti-Nucleophosmin 1 Autoantibody as a Potential Biomarker in European-American and African-American Patients With Prostate Cancer. Prostate. 2016;76:1375-86 pubmed publisher
Liu M, Varela Ramirez A, Li J, Dai L, Aguilera R, Zhang J. Humoral autoimmune response to nucleophosmin in the immunodiagnosis of hepatocellular carcinoma. Oncol Rep. 2015;33:2245-52 pubmed publisher
Musinova Y, Kananykhina E, Potashnikova D, Lisitsyna O, Sheval E. A charge-dependent mechanism is responsible for the dynamic accumulation of proteins inside nucleoli. Biochim Biophys Acta. 2015;1853:101-10 pubmed publisher
Jahn S, LAW M, Corsino P, Rowe T, Davis B, Law B. Assembly, activation, and substrate specificity of cyclin D1/Cdk2 complexes. Biochemistry. 2013;52:3489-501 pubmed publisher
Wang W, Budhu A, Forgues M, Wang X. Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication. Nat Cell Biol. 2005;7:823-30 pubmed
product information
Catalog Number :
17578
Product Name :
GFP-NPM WT
article :
doi10.1038/ncb1282
id1014
pubmed_id16041368
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C2
backbone_mutation
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
B23.1
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesB23, NPM
geneNPM1
id4869
genbank_ids
mutation
nameNPM
shRNA_sequence
size900
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagEGFP
locationN terminal on insert
tagFlag
plasmid copy :
K. Nagata (U of Tsukuba, Japan)
resistance markers :
562
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA