This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMKO shRNA Bim
catalog :
17235
citations: 3
Reference
Wang L, Hensch N, Bondra K, Sreenivas P, Zhao X, Chen J, et al. SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation. Cancer Res. 2021;81:5451-5463 pubmed publisher
Horiuchi D, Kusdra L, Huskey N, Chandriani S, Lenburg M, Gonzalez Angulo A, et al. MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J Exp Med. 2012;209:679-96 pubmed publisher
Schmelzle T, Mailleux A, Overholtzer M, Carroll J, Solimini N, Lightcap E, et al. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proc Natl Acad Sci U S A. 2007;104:3787-92 pubmed
product information
Catalog Number :
17235
Product Name :
pMKO shRNA Bim
article :
doi10.1073/pnas.0700115104
id1904
pubmed_id17360431
bacterial resistance :
Ampicillin
cloning :
backbonepMKO.1
backbone_mutation
backbone_originAvailable at Addgene (#8452)
backbone_size6700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
RNAi
growth notes :
see article supplementary materials for shRNA seequence
origin :
37
pi :
alt_names
Bim
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5AgeI
promoter
sequencing_primer_3
sequencing_primer_5pLXSN 5'
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesBAM, BIM, BOD
geneBCL2L11
id10018
genbank_ids
mutation
nameBim shRNA
shRNA_sequence
size60
species
9606
Homo sapiens
tags
resistance markers :
52
tags :
Unknown
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA