This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMIG-hSOX2
catalog :
17226
citations: 10
Reference
Chia P, Zhong F, Niwa S, Bonnard C, Utami K, Zeng R, et al. A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability. elife. 2018;7: pubmed publisher
Szenker Ravi E, Altunoglu U, Leushacke M, Bosso Lefèvre C, Khatoo M, Thi Tran H, et al. RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018;557:564-569 pubmed publisher
Trevisan M, Desole G, Costanzi G, Lavezzo E, Palu G, Barzon L. Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2017;18: pubmed publisher
Villa Diaz L, Kim J, Laperle A, Palecek S, Krebsbach P. Inhibition of Focal Adhesion Kinase Signaling by Integrin ?6?1 Supports Human Pluripotent Stem Cell Self-Renewal. Stem Cells. 2016;34:1753-64 pubmed publisher
Boza Morán M, Martínez Hernández R, Bernal S, Wanisch K, Also Rallo E, Le Heron A, et al. Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons. Sci Rep. 2015;5:11696 pubmed publisher
Madison J, Zhou F, Nigam A, Hussain A, Barker D, Nehme R, et al. Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities. Mol Psychiatry. 2015;20:703-17 pubmed publisher
Ingrungruanglert P, Amarinthnukrowh P, Rungsiwiwut R, Maneesri le Grand S, Sosothikul D, Suphapeetiporn K, et al. Wiskott-Aldrich syndrome iPS cells produce megakaryocytes with defects in cytoskeletal rearrangement and proplatelet formation. Thromb Haemost. 2015;113:792-805 pubmed publisher
Wezel F, Pearson J, Kirkwood L, Southgate J. Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer. Am J Pathol. 2013;183:1128-1136 pubmed publisher
Pirozhkova I, Barat A, Dmitriev P, Kim E, Robert T, Guégan J, et al. Differences in transcription patterns between induced pluripotent stem cells produced from the same germ layer are erased upon differentiation. PLoS ONE. 2013;8:e53033 pubmed publisher
Park I, Zhao R, West J, Yabuuchi A, Huo H, Ince T, et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature. 2008;451:141-6 pubmed
product information
Catalog Number :
17226
Product Name :
pMIG-hSOX2
article :
doi10.1038/nature06534
id1894
pubmed_id18157115
bacterial resistance :
Ampicillin
cloning :
backbonepMIG
backbone_mutation
backbone_origin
backbone_size6500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
Addgene has confirmed the presence of GFP in the pMIG vector backbone by sequencing, but the functionality of the GFP has not been confirmed. Please visit www.addgene.org/18119 to find the paper in which the pMIG-cMyc was used
origin :
37
pi :
alt_names
SOX2
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5pLXSN 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesANOP3, MCOPS3
geneSOX2
id6657
genbank_ids
mutation
nameSRY (sex determining region Y)-box 2
shRNA_sequence
size954
species
9606
Homo sapiens
tags
resistance markers :
101
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA