This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMIG-hOCT4
catalog :
17225
citations: 8
Reference
Chia P, Zhong F, Niwa S, Bonnard C, Utami K, Zeng R, et al. A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability. elife. 2018;7: pubmed publisher
Szenker Ravi E, Altunoglu U, Leushacke M, Bosso Lefèvre C, Khatoo M, Thi Tran H, et al. RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018;557:564-569 pubmed publisher
Trevisan M, Desole G, Costanzi G, Lavezzo E, Palu G, Barzon L. Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2017;18: pubmed publisher
Boza Morán M, Martínez Hernández R, Bernal S, Wanisch K, Also Rallo E, Le Heron A, et al. Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons. Sci Rep. 2015;5:11696 pubmed publisher
Madison J, Zhou F, Nigam A, Hussain A, Barker D, Nehme R, et al. Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities. Mol Psychiatry. 2015;20:703-17 pubmed publisher
Ingrungruanglert P, Amarinthnukrowh P, Rungsiwiwut R, Maneesri le Grand S, Sosothikul D, Suphapeetiporn K, et al. Wiskott-Aldrich syndrome iPS cells produce megakaryocytes with defects in cytoskeletal rearrangement and proplatelet formation. Thromb Haemost. 2015;113:792-805 pubmed publisher
Pirozhkova I, Barat A, Dmitriev P, Kim E, Robert T, Guégan J, et al. Differences in transcription patterns between induced pluripotent stem cells produced from the same germ layer are erased upon differentiation. PLoS ONE. 2013;8:e53033 pubmed publisher
Park I, Zhao R, West J, Yabuuchi A, Huo H, Ince T, et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature. 2008;451:141-6 pubmed
product information
Catalog Number :
17225
Product Name :
pMIG-hOCT4
article :
doi10.1038/nature06534
id1894
pubmed_id18157115
bacterial resistance :
Ampicillin
cloning :
backbonepMIG
backbone_mutation
backbone_origin
backbone_size6500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
Addgene has confirmed the presence of GFP in the pMIG vector backbone by sequencing, but the functionality of the GFP has not been confirmed. Note: Visit www.addgene.org/18119 to find the pMIG-cMyc used in this paper
origin :
37
pi :
alt_names
OCT4
cloning
clone_methodRestriction Enzyme
cloning_site_3BglII
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5pLXSN 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesOCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4, Oct3/4
genePOU5F1
id5460
genbank_ids
mutation
namePOU class 5 homeobox 1
shRNA_sequence
size1083
species
9606
Homo sapiens
tags
resistance markers :
101
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA