This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
phOCT4-Luc
catalog :
17221
citations: 9
Reference
Tan A, PRASAD R, Jho E. TFEB regulates pluripotency transcriptional network in mouse embryonic stem cells independent of autophagy-lysosomal biogenesis. Cell Death Dis. 2021;12:343 pubmed publisher
Feng J, Lan R, Cai G, Lin J. TREX1 suppression imparts cancer-stem-cell-like characteristics to CD133- osteosarcoma cells through the activation of E2F4 signaling. Int J Clin Exp Pathol. 2019;12:1134-1153 pubmed
Wang R, Bhattacharya R, Ye X, Fan F, Boulbés D, Xia L, et al. Endothelial cells activate the cancer stem cell-associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion. Mol Oncol. 2017;11:1023-1034 pubmed publisher
Ferreyra Solari N, Belforte F, Canedo L, Videla Richardson G, Espinosa J, Rossi M, et al. The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis. Cancer Res. 2016;76:5383-94 pubmed publisher
Mali P, Aach J, Stranges P, Esvelt K, Moosburner M, Kosuri S, et al. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat Biotechnol. 2013;31:833-8 pubmed publisher
Wang W, Tzeng T, Wang J, Lee D, Lin Y, Wu P, et al. The EP300, KDM5A, KDM6A and KDM6B chromatin regulators cooperate with KLF4 in the transcriptional activation of POU5F1. PLoS ONE. 2012;7:e52556 pubmed publisher
Kim R, Park J, Roh K, Choi A, Kim S, Kim P, et al. High aldehyde dehydrogenase activity enhances stem cell features in breast cancer cells by activating hypoxia-inducible factor-2?. Cancer Lett. 2013;333:18-31 pubmed publisher
Kumar S, Liu S, Lu H, Zhang H, Zhang P, Gimotty P, et al. Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene. 2012;31:4898-911 pubmed publisher
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-72 pubmed
product information
Catalog Number :
17221
Product Name :
phOCT4-Luc
article :
doi10.1016/j.cell.2007.11.019
id1893
pubmed_id18035408
bacterial resistance :
Ampicillin
cloning :
backbonepGV-BM2
backbone_mutation
backbone_origin
backbone_size4842
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BglII
cloning_site_5KpnI
promoter
sequencing_primer_3LucNRev (CCTTATGCAGTTGCTCTCC)
sequencing_primer_5RVprimer3 (CTAGCAAAATAGGCTGTCCC)
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesOCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4, Oct3/4
genePOU5F1
id5460
genbank_ids
mutation
nameUpstream region of human OCT4
shRNA_sequence
size5068
species
9606
Homo sapiens
tags
resistance markers :
596
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA