This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
lentiCRISPR v2 puro - CRBN (#2)
catalog :
166241
citations: 1
Reference
Lier S, Sellmer A, Orben F, Heinzlmeir S, Kraus L, Schneeweis C, et al. A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer. Bioorg Chem. 2021;:105505 pubmed publisher
product information
Catalog Number :
166241
Product Name :
lentiCRISPR v2 puro - CRBN (#2)
article :
doi10.1016/j.bioorg.2021.105505
id28215986
pubmed_id34838332
bacterial resistance :
Ampicillin
cloning :
backbonelentiCRISPR v2
backbone_mutation
backbone_origin
backbone_size14877
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
CRISPR
growth strain :
sgRNA (#2) to generate a knockout of human CRBN by targeting the start region of Exon1
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BsmBI
cloning_site_5BsmBI
promoter
sequencing_primer_3
sequencing_primer_5GAGGGCCTATTTCCC
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesMRT2, MRT2A
geneCRBN
id51185
genbank_ids
NM_016302
mutation
nameCRBN
shRNA_sequenceGCAGGACGCTGCGCACAACA
size
species
9606
Homo sapiens
tags
resistance markers :
5284
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA