This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGL3-OF (mutant TCF-4 sites)
catalog :
16559
citations: 11
Reference
Liu B, Zhang R, Zhu Y, Hao R. Exosome-derived microRNA-433 inhibits tumorigenesis through incremental infiltration of CD4 and CD8 cells in non-small cell lung cancer. Oncol Lett. 2021;22:607 pubmed publisher
He S, Wang W, Wan Z, Shen H, Zhao Y, You Z, et al. FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway. Oncogenesis. 2021;10:6 pubmed publisher
Ping M. Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling. Cancer Manag Res. 2020;12:11773-11782 pubmed publisher
Zheng L, Liang X, Li S, Li T, Shang W, Ma L, et al. CHAF1A interacts with TCF4 to promote gastric carcinogenesis via upregulation of c-MYC and CCND1 expression. EBioMedicine. 2018;38:69-78 pubmed publisher
Zhang T, Ma Z, Liu L, Sun J, Tang H, Zhang B, et al. DDX39 promotes hepatocellular carcinoma growth and metastasis through activating Wnt/?-catenin pathway. Cell Death Dis. 2018;9:675 pubmed publisher
Lahdaoui F, Messager M, Vincent A, Hec F, Gandon A, Warlaumont M, et al. Depletion of MUC5B mucin in gastrointestinal cancer cells alters their tumorigenic properties: implication of the Wnt/?-catenin pathway. Biochem J. 2017;474:3733-3746 pubmed publisher
Hu S, Zheng Q, Wu H, Wang C, Liu T, Zhou W. miR-532 promoted gastric cancer migration and invasion by targeting NKD1. Life Sci. 2017;177:15-19 pubmed publisher
Wang Q, Lu P, Shi Z, Xu Y, Xiang J, Wang Y, et al. Glucocorticoid Receptor β Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation. Mol Neurobiol. 2015;52:1106-1118 pubmed publisher
Ding Z, Liang H, Jin G, Chen W, Wang W, Datta P, et al. Smad6 suppresses the growth and self-renewal of hepatic progenitor cells. J Cell Physiol. 2014;229:651-60 pubmed publisher
Shen G, Jia H, Tai Q, Li Y, Chen D. miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma. Carcinogenesis. 2013;34:211-9 pubmed publisher
Shih I, Yu J, He T, Vogelstein B, Kinzler K. The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Cancer Res. 2000;60:1671-6 pubmed
product information
Catalog Number :
16559
Product Name :
pGL3-OF (mutant TCF-4 sites)
article :
doi
id1859
pubmed_id10749138
bacterial resistance :
Ampicillin
cloning :
backbonepGL3-Basic
backbone_mutation
backbone_originPromega
backbone_size4800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
TCF-4 mutant binding sequence - CCTTTGGC
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5XhoI
promoter
sequencing_primer_3LucNrev
sequencing_primer_5RVprimer3
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCDG2T, E2-2, FCD2, FECD3, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, TCF-4, bHLHb19
geneTCF4
id6925
genbank_ids
mutation3 copies of mutant Tcf-4 binding sites
nameTCF-4 binding sites
shRNA_sequence
size100
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagLuciferase
resistance markers :
553
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA