This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCI-neo beta catenin S33Y
catalog :
16519
citations: 6
Reference
Pavlaki I, Shapiro M, Pisignano G, Jones S, Telenius J, Muñoz Descalzo S, et al. Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells. PLoS Genet. 2022;18:e1010230 pubmed publisher
Spitzner M, Emons G, Schütz K, Wolff H, Rieken S, Ghadimi B, et al. Inhibition of Wnt/β-Catenin Signaling Sensitizes Esophageal Cancer Cells to Chemoradiotherapy. Int J Mol Sci. 2021;22: pubmed publisher
Zhu L, Jones C. The canonical Wnt/β-catenin signaling pathway stimulates herpes simplex virus 1 productive infection. Virus Res. 2018;256:29-37 pubmed publisher
Zhu L, Workman A, Jones C. Potential Role for a β-Catenin Coactivator (High-Mobility Group AT-Hook 1 Protein) during the Latency-Reactivation Cycle of Bovine Herpesvirus 1. J Virol. 2017;91: pubmed publisher
Liu Y, Hancock M, Workman A, Doster A, Jones C. β-Catenin, a Transcription Factor Activated by Canonical Wnt Signaling, Is Expressed in Sensory Neurons of Calves Latently Infected with Bovine Herpesvirus 1. J Virol. 2016;90:3148-59 pubmed publisher
Morin P, Sparks A, Korinek V, Barker N, Clevers H, Vogelstein B, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997;275:1787-90 pubmed
product information
Catalog Number :
16519
Product Name :
pCI-neo beta catenin S33Y
article :
doi10.1126/science.275.5307.1787
id1847
pubmed_id9065402
bacterial resistance :
Ampicillin
cloning :
backbonepCI-neo
backbone_mutation
backbone_originPromega
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
SW48 has a C-to-A missense mutation that changes Ser33 to Tyr. Note that the NheI site is not intact and cannot be used for sub-cloning.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5XhoI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed1
entrez_gene
aliasesCTNNB, EVR7, MRD19, NEDSDV, armadillo
geneCTNNB1
id1499
genbank_ids
mutationS33Y (SW48 mutation)
namebeta catenin
shRNA_sequence
size2350
species
9606
Homo sapiens
tags
resistance markers :
553
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA