This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
PKC beta I WT
catalog :
16378
citations: 5
Reference
Niemeyer A, Rinne A, Kienitz M. Receptor-specific regulation of atrial GIRK channel activity by different Ca2+-dependent PKC isoforms. Cell Signal. 2019;64:109418 pubmed publisher
Wallroth A, Koch P, Marat A, Krause E, Haucke V. Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signalling via mTORC1. Nat Cell Biol. 2019;21:1093-1101 pubmed publisher
Schaffer T, Smith J, Cook E, Phan T, Margolis S. PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 2018;25:2470-2483.e8 pubmed publisher
Evensen N, Kuscu C, Nguyen H, Zarrabi K, Dufour A, Kadam P, et al. Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration. J Natl Cancer Inst. 2013;105:1402-16 pubmed publisher
Soh J, Weinstein I. Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes. J Biol Chem. 2003;278:34709-16 pubmed
product information
Catalog Number :
16378
Product Name :
PKC beta I WT
article :
doi10.1074/jbc.M302016200
id1812
pubmed_id12794082
bacterial resistance :
Ampicillin
cloning :
backbonepHACE
backbone_mutation
backbone_origin
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
From user-provided sequence (see 'Reviews'), there are five amino acid differences from one of two NCBI reference sequences (AAA41868.1 and NP_001165776.1): 25A, 62F, 64K, 69C, and 294G. These mutations are also present in human, bovine, and xenopus sequences and are therefore not believed to affect function.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPkcb, Prkcb1
genePrkcb
id25023
genbank_ids
mutation
namePKC beta 1
shRNA_sequence
size2013
species
10116
Rattus norvegicus
tags
locationC terminal on backbone
tagHA
resistance markers :
569
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA