This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5 beta1
catalog :
16042
citations: 5
Reference
Iwashita J, Murata J. Integrin β1 subunit regulates cellular and secreted MUC5AC and MUC5B production in NCI-H292 human lung epithelial cells. Biochem Biophys Rep. 2021;28:101124 pubmed publisher
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, et al. Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Nat Mater. 2020;19:797-806 pubmed publisher
Jahangiri A, Nguyen A, Chandra A, Sidorov M, Yagnik G, Rick J, et al. Cross-activating c-Met/?1 integrin complex drives metastasis and invasive resistance in cancer. Proc Natl Acad Sci U S A. 2017;114:E8685-E8694 pubmed publisher
Goto K, Takemura G, Takahashi T, Okada H, Kanamori H, Kawamura I, et al. Intravenous Administration of Endothelial Colony-Forming Cells Overexpressing Integrin β1 Augments Angiogenesis in Ischemic Legs. Stem Cells Transl Med. 2016;5:218-26 pubmed publisher
Giancotti F, Ruoslahti E. Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell. 1990;60:849-59 pubmed
product information
Catalog Number :
16042
Product Name :
pRK5 beta1
article :
doi10.1016/0092-8674(90)90098-Y
id1707
pubmed_id2155708
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Please note that the beta-1 integrin ORF has the following amino acid changes - C17G, M170T and N227S. Addgene is not aware of the impact of these mutations on the plasmid function.
origin :
37
pi :
alt_names
beta 1 integrin
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
geneITGB1
id3688
genbank_ids
mutation
namebeta1
shRNA_sequence
size3600
species
9606
Homo sapiens
tags
resistance markers :
165
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA